Protein Domain : IPR013785

Type:  Domain Name:  Aldolase-type TIM barrel
Description:  This entry represents the TIM beta/alpha barrel found in aldolase and in related proteins. This TIM barrel usually covers the entire protein structure. Proteins containing this TIM barrel domain include class I aldolases, class I DAHP synthases, class II fructose-bisphosphate aldolases (FBP aldolases), and 5-aminolaevulinate dehydratase (a hybrid of classes I and II aldolases) [, , ]. Short Name:  Aldolase_TIM

13 Child Features

DB identifier Type Name
IPR002932 Domain Glutamate synthase domain
IPR006218 Domain DAHP synthetase I/KDSA
IPR000262 Domain FMN-dependent dehydrogenase
IPR009215 Domain TIM-barrel domain, IGPS-like
IPR011060 Domain Ribulose-phosphate binding barrel
IPR006982 Domain Glutamate synthase, central-N
IPR022998 Domain Thiamin phosphate synthase superfamily
IPR001155 Domain NADH:flavin oxidoreductase/NADH oxidase, N-terminal
IPR000891 Domain Pyruvate carboxyltransferase
IPR001093 Domain IMP dehydrogenase/GMP reductase
IPR002638 Domain Quinolinate phosphoribosyl transferase, C-terminal
IPR004136 Domain Nitronate monooxygenase
IPR013132 Domain N-acetylneuraminic acid synthase, N-terminal

16 Contains

DB identifier Type Name
IPR006638 Domain Elongator protein 3/MiaB/NifB
IPR018508 Active_site 3-dehydroquinate dehydratase, active site
IPR018517 Conserved_site tRNA-dihydrouridine synthase, conserved site
IPR000385 Conserved_site MoaA/nifB/pqqE, iron-sulphur binding, conserved site
IPR001468 Conserved_site Indole-3-glycerol phosphate synthase, conserved site
IPR018225 Active_site Transaldolase, active site
IPR018204 Active_site Tryptophan synthase, alpha chain, active site
IPR002034 Conserved_site Alpha-isopropylmalate/homocitrate synthase, conserved site
IPR020624 Conserved_site Schiff base-forming aldolase, conserved site
IPR020625 Active_site Schiff base-forming aldolase, active site
IPR018089 Active_site Orotidine 5'-phosphate decarboxylase, active site
IPR000138 Active_site Hydroxymethylglutaryl-CoA lyase, active site
IPR008259 Active_site FMN-dependent alpha-hydroxy acid dehydrogenase, active site
IPR001295 Conserved_site Dihydroorotate dehydrogenase, conserved site
IPR020861 Active_site Triosephosphate isomerase, active site
IPR015875 Conserved_site IMP dehydrogenase / GMP reductase, conserved site

1 Cross References

Identifier
G3DSA:3.20.20.70

48 Found Ins

DB identifier Type Name
IPR005671 Family 2-isopropylmalate synthase, bacterial-type
IPR012220 Family Glutamate synthase, eukaryotic
IPR002241 Family Glycoside hydrolase, family 27
IPR003698 Family Lipoyl synthase
IPR019939 Family CofG family
IPR019940 Family CofH family
IPR020050 Family FO synthase, subunit 2
IPR003733 Family Thiamine phosphate synthase
IPR005839 Family Methylthiotransferase
IPR006466 Family MiaB-like tRNA modifying enzyme, archaeal-type
IPR005675 Family Citramalate synthase
IPR013483 Family Molybdenum cofactor biosynthesis protein A
IPR004393 Family Nicotinate-nucleotide pyrophosphorylase
IPR017629 Family 4-hydroxy-2-oxovalerate aldolase
IPR002252 Family Glycoside hydrolase, family 36
IPR014640 Family Imidazole glycerol phosphate synthase HisHF
IPR005930 Family Pyruvate carboxylase
IPR005840 Family Ribosomal protein S12 methylthiotransferase RimO
IPR006463 Family tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
IPR018155 Family Hyaluronidase
IPR005668 Family 2-isopropylmalate synthase
IPR020030 Family Pseudaminic acid biosynthesis, PseI
IPR004652 Family tRNA-dihydrouridine synthase, TIM-barrel, NifR3
IPR020007 Family N-acetylneuraminate synthase
IPR005776 Family Oxaloacetate decarboxylase, alpha subunit
IPR006242 Family Putative pyrophosphorylase ModD
IPR005911 Family Conserved hypothetical protein CHP01212
IPR008289 Family Pentafunctional AroM protein
IPR006467 Family MiaB-like tRNA modifying enzyme
IPR016779 Family Radical SAM enzyme, MSMEG0568

1 GO Annotation

GO Term Gene Name
GO:0003824 IPR013785

1 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR013785

0 Parent Features

53644 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
92339 D8RFU7 PAC:15417656 Selaginella moellendorffii 984  
92851 D8RG32 PAC:15421367 Selaginella moellendorffii 87  
236575 D8TAS2 PAC:15409898 Selaginella moellendorffii 449  
270843 D8RGM8 PAC:15423275 Selaginella moellendorffii 376  
267384 D8RHM0 PAC:15410634 Selaginella moellendorffii 358  
411189 D8RGV0 PAC:15406369 Selaginella moellendorffii 325  
411824 D8RJ53 PAC:15411656 Selaginella moellendorffii 238  
96980 D8RLD7 PAC:15411738 Selaginella moellendorffii 351  
270960 D8RMI6 PAC:15401846 Selaginella moellendorffii 303  
441764 D8RMF2 PAC:15410273 Selaginella moellendorffii 237  
97357 D8RMI5 PAC:15409984 Selaginella moellendorffii 279  
165452 D8QUP9 PAC:15413520 Selaginella moellendorffii 389  
79056 D8QWC0 PAC:15421338 Selaginella moellendorffii 386  
413264 D8RNW2 PAC:15413014 Selaginella moellendorffii 500  
441909 D8RNN6 PAC:15411644 Selaginella moellendorffii 418  
51736 D8RPD2 PAC:15411325 Selaginella moellendorffii 354  
173572 D8RRK2 PAC:15415678 Selaginella moellendorffii 390  
174143 D8RTK6 PAC:15415497 Selaginella moellendorffii 319  
414490 D8RSY2 PAC:15417501 Selaginella moellendorffii 164  
267769 D8RTU3 PAC:15413653 Selaginella moellendorffii 348  
267738 D8RT35 PAC:15413569 Selaginella moellendorffii 331  
165887 D8QXQ4 PAC:15416559 Selaginella moellendorffii 406  
230186 D8QXN0 PAC:15411676 Selaginella moellendorffii 382  
166200 D8QWS7 PAC:15414826 Selaginella moellendorffii 223  
438600 D8QWZ6 PAC:15422527 Selaginella moellendorffii 411  
79855 D8QX69 PAC:15405179 Selaginella moellendorffii 871  
105201 D8RZ21 PAC:15413343 Selaginella moellendorffii 198  
271184 D8RYP1 PAC:15420974 Selaginella moellendorffii 301  
228435 D8S0X1 PAC:15407565 Selaginella moellendorffii 283  
443602 D8S2T4 PAC:15415211 Selaginella moellendorffii 378  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9406553
            12741828
            15476818