Protein Domain : IPR008289

Type:  Family Name:  Pentafunctional AroM protein
Description:  Each member of this group contains five functional domains catalysing five sequential steps of the shikimate pathway. Each domain corresponds to a monofunctional prokaryotic enzyme of the same pathway: 3-dehydroquinate synthase, 3-dehydroquinate dehydratase, shikimate 5-dehydrogenase, shikimate kinase, and 3-phosphoshikimate 1-carboxyvinyltransferase. The multifunctional gene is regulated in response to amino acid limitation by coordinate regulation, which provides an economical means of simultaneously synthesizing five shikimate pathway enzymes []. Short Name:  Pentafunct_AroM
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0 Child Features

5 Contains

DB identifier Type Name
IPR013708 Domain Shikimate dehydrogenase substrate binding, N-terminal
IPR013785 Domain Aldolase-type TIM barrel
IPR016040 Domain NAD(P)-binding domain
IPR018508 Active_site 3-dehydroquinate dehydratase, active site
IPR010110 Domain Shikimate dehydrogenase, AroM-type

2 Cross Referencess

Identifier
PIRSF000514
MF_03143

0 Found In

8 GO Annotations

GO Term Gene Name
GO:0003855 IPR008289
GO:0003856 IPR008289
GO:0003866 IPR008289
GO:0004764 IPR008289
GO:0004765 IPR008289
GO:0005524 IPR008289
GO:0009073 IPR008289
GO:0055114 IPR008289

8 Ontology Annotations

GO Term Gene Name
GO:0003855 IPR008289
GO:0003856 IPR008289
GO:0003866 IPR008289
GO:0004764 IPR008289
GO:0004765 IPR008289
GO:0005524 IPR008289
GO:0009073 IPR008289
GO:0055114 IPR008289

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2848727