| Type: | Family | Name: | Glycoside hydrolase, family 36 |
| Description: | O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Glycoside hydrolase family 36 comprises enzymes with only one known activity; alpha-galactosidase ().Alpha-galactosidase (melibiase) catalyses the hydrolysis of melibiose into galactose and glucose []. In man, deficiency in the enzyme results inFabry's disease (X-linked sphingolipidosis). An Escherichia coliplasmid-encoded alpha-galactosidase (rafA) [] contains a region of about 50 amino acidsthat is similar to a domain of the eukaryotic alpha-galactosidases. | Short Name: | Glyco_hydro_36 |
