Protein Domain : IPR005839

Type:  Family Name:  Methylthiotransferase
Description:  This family contains four subfamilies, and includes the tRNA-i(6)A37 modification enzyme, MiaB (). The other three subfamilies are modelled by , and . Together, the four subfamilies hit every sequence hit by the family model without any overlap between them.MiaB acts on a particular isoprenylated Adenine base of certain tRNAs causing thiolation at an aromatic carbon, and probably also transferring a methyl group from SAM to the thiol. The particular substrate of the three other subfamilies is unknown but may be very closely related. Short Name:  Methylthiotransferase
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4 Child Features

DB identifier Type Name
IPR006466 Family MiaB-like tRNA modifying enzyme, archaeal-type
IPR005840 Family Ribosomal protein S12 methylthiotransferase RimO
IPR006463 Family tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
IPR006467 Family MiaB-like tRNA modifying enzyme

5 Contains

DB identifier Type Name
IPR013785 Domain Aldolase-type TIM barrel
IPR006638 Domain Elongator protein 3/MiaB/NifB
IPR002792 Domain TRAM domain
IPR013848 Domain Methylthiotransferase, N-terminal
IPR020612 Conserved_site Methylthiotransferase, conserved site

1 Cross References

Identifier
TIGR00089

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016740 IPR005839
GO:0051539 IPR005839
GO:0043412 IPR005839

3 Ontology Annotations

GO Term Gene Name
GO:0016740 IPR005839
GO:0051539 IPR005839
GO:0043412 IPR005839

1 Parent Features

DB identifier Type Name
IPR023970 Family Methylthiotransferase/radical SAM-type protein

748 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
31574 D8RF06 PAC:15417785 Selaginella moellendorffii 421  
180500 D8SKD9 PAC:15414005 Selaginella moellendorffii 469  
evm.model.supercontig_6.187 PAC:16423361 Carica papaya 405  
evm.model.supercontig_66.10 PAC:16424542 Carica papaya 634  
30074.m001410 B9S747 PAC:16816971 Ricinus communis 630  
29634.m002060 B9S686 PAC:16804201 Ricinus communis 535  
Cucsa.184640.1 PAC:16967583 Cucumis sativus 521  
Cucsa.061610.1 PAC:16954908 Cucumis sativus 635  
orange1.1g041524m A0A067FUI9 PAC:18098745 Citrus sinensis 524  
orange1.1g006956m A0A067GWL8 PAC:18091348 Citrus sinensis 624  
orange1.1g006836m A0A067GZA4 PAC:18091347 Citrus sinensis 629  
orange1.1g007001m A0A067GWA9 PAC:18091349 Citrus sinensis 622  
orange1.1g010162m A0A067H8T6 PAC:18091350 Citrus sinensis 516  
orange1.1g013195m A0A067H8F9 PAC:18091352 Citrus sinensis 448  
orange1.1g012929m A0A067GWB4 PAC:18091351 Citrus sinensis 453  
AT4G36390.1 Q8H0V1 PAC:19645627 Arabidopsis thaliana 640  
AT1G72090.1 Q9C7H2 PAC:19658225 Arabidopsis thaliana 601  
Thhalv10024669m V4P269 PAC:20193657 Eutrema salsugineum 632  
Thhalv10025020m V4LS77 PAC:20193658 Eutrema salsugineum 491  
Thhalv10000077m V4M2D4 PAC:20208263 Eutrema salsugineum 647  
Thhalv10000140m V4L7P6 PAC:20208264 Eutrema salsugineum 500  
Thhalv10000144m V4LRD8 PAC:20208265 Eutrema salsugineum 493  
Thhalv10018307m V4KAB8 PAC:20192110 Eutrema salsugineum 603  
Ciclev10000888m V4T416 PAC:20785912 Citrus clementina 516  
Ciclev10001135m V4SJM2 PAC:20785913 Citrus clementina 448  
Ciclev10000582m V4V758 PAC:20785911 Citrus clementina 629  
Lus10016926 PAC:23159604 Linum usitatissimum 610  
Lus10041793 PAC:23146973 Linum usitatissimum 630  
Lus10028344 PAC:23166025 Linum usitatissimum 628  
Potri.007G018500.1 B9HFB0 PAC:27014699 Populus trichocarpa 623  

0 Publications