Protein Domain : IPR020050

Type:  Family Name:  FO synthase, subunit 2
Description:  FO synthase catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) []. This entry represents CofH/subunit 2 of FO synthase, it binds 1 4Fe-4S cluster, which is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.Although this entry contains CofH/subunit2 of coenzyme F(420) biosynthesis it appears to hit genomes more broadly than just the subset that make coenzyme F(420), so that narrower group is being built as a separate family (). Short Name:  FO_synthase_su2
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3 Child Features

DB identifier Type Name
IPR019940 Family CofH family
IPR022431 Family Cyclic dehypoxanthine futalosine synthase
IPR022432 Family Aminodeoxyfutalosine synthase

2 Contains

DB identifier Type Name
IPR013785 Domain Aldolase-type TIM barrel
IPR007197 Domain Radical SAM

1 Cross References

Identifier
TIGR00423

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0016765 IPR020050

1 Ontology Annotations

GO Term Gene Name
GO:0016765 IPR020050

1 Parent Features

DB identifier Type Name
IPR005244 Family FO synthase, subunit 2-like

42 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
409429 D8RBF3 PAC:15402378 Selaginella moellendorffii 796  
15789 I0YXI6 PAC:27392518 Coccomyxa subellipsoidea C-169 783  
60554 C1MZ03 PAC:27344059 Micromonas pusilla CCMP1545 1011  
83126 C1E7Q0 PAC:27401805 Micromonas sp RCC299 874  
51122 A4S5K0 PAC:27417084 Ostreococcus lucimarinus 841  
Cre17.g741250.t1.1 E0YRV5 PAC:30782245 Chlamydomonas reinhardtii 1106  
Sphfalx0023s0089.2.p PAC:32621435 Sphagnum fallax 691  
Sphfalx0023s0089.1.p PAC:32621434 Sphagnum fallax 956  
Pp3c3_8520V3.2.p PAC:32942401 Physcomitrium patens 676  
Pp3c3_8520V3.1.p A0A2K1KTP1 PAC:32942398 Physcomitrium patens 905  
Pp3c3_8520V3.3.p A0A2K1KTP1 PAC:32942399 Physcomitrium patens 905  
Pp3c3_8520V3.4.p PAC:32942400 Physcomitrium patens 869  
Mapoly0032s0121.1.p A0A2R6X775 PAC:33011652 Marchantia polymorpha 895  
Mapoly0032s0121.2.p A0A2R6X779 PAC:33011653 Marchantia polymorpha 780  
Bobra.113_1s0059.1.p PAC:40723871 Botryococcus braunii 915  
Bobra.113_1s0059.2.p PAC:40723872 Botryococcus braunii 914  
Sphmag17G043100.2.p PAC:41912117 Sphagnum magellanicum 872  
Sphmag17G043100.4.p PAC:41912118 Sphagnum magellanicum 872  
Sphmag17G043100.7.p PAC:41912116 Sphagnum magellanicum 952  
Sphmag17G043100.3.p PAC:41912119 Sphagnum magellanicum 870  
Sphmag17G043100.8.p PAC:41912111 Sphagnum magellanicum 954  
Sphmag17G043100.9.p PAC:41912112 Sphagnum magellanicum 954  
Sphmag17G043100.11.p PAC:41912110 Sphagnum magellanicum 955  
Sphmag17G043100.6.p PAC:41912115 Sphagnum magellanicum 952  
Sphmag17G043100.1.p PAC:41912109 Sphagnum magellanicum 957  
Sphmag17G043100.5.p PAC:41912114 Sphagnum magellanicum 952  
Sphmag17G043100.10.p PAC:41912113 Sphagnum magellanicum 954  
Sphfalx17G047900.1.p PAC:41982671 Sphagnum fallax 956  
Sphfalx17G047900.2.p PAC:41982674 Sphagnum fallax 691  
Sphfalx17G047900.5.p PAC:41982673 Sphagnum fallax 907  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14593448