Protein Domain : IPR007197

Type:  Domain Name:  Radical SAM
Description:  Radical SAM proteins catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. Evidence exists that these proteins generate a radical species by reductive cleavage of S:-adenosylmethionine (SAM) through an unusual Fe-S centre [, ]. Short Name:  rSAM
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1 Child Features

DB identifier Type Name
IPR006638 Domain Elongator protein 3/MiaB/NifB

3 Contains

DB identifier Type Name
IPR020612 Conserved_site Methylthiotransferase, conserved site
IPR000385 Conserved_site MoaA/nifB/pqqE, iron-sulphur binding, conserved site
IPR001989 Conserved_site Radical-activating enzyme, conserved site

1 Cross References

Identifier
PF04055

16 Found Ins

DB identifier Type Name
IPR004383 Family Ribosomal RNA large subunit methyltransferase RlmN/Cfr
IPR019939 Family CofG family
IPR019940 Family CofH family
IPR020050 Family FO synthase, subunit 2
IPR003739 Family Lysine-2,3-aminomutase/glutamate 2,3-aminomutase
IPR017742 Family 7-carboxy-7-deazaguanine synthase
IPR012839 Family Glycyl radical enzyme activase
IPR012838 Family Pyruvate formate-lyase activating enzyme
IPR022447 Family Lysine-2,3-aminomutase-related
IPR022459 Family Lysine-2,3-aminomutase
IPR016771 Family Fe-S oxidoreductase, radical SAM domain-containing, TM0948, predicted
IPR016863 Family dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase
IPR012726 Family Thiazole biosynthesis ThiH
IPR012837 Family Ribonucleoside-triphosphate reductase activating, anaerobic
IPR012840 Family Ribonucleoside-triphosphate reductase, anaerobic-like
IPR022432 Family Aminodeoxyfutalosine synthase

2 GO Annotations

GO Term Gene Name
GO:0003824 IPR007197
GO:0051536 IPR007197

2 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR007197
GO:0051536 IPR007197

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
31574 D8RF06 PAC:15417785 Selaginella moellendorffii 421  
412711 D8RL87 PAC:15413852 Selaginella moellendorffii 469  
96899 D8RL74 PAC:15411019 Selaginella moellendorffii 557  
79056 D8QWC0 PAC:15421338 Selaginella moellendorffii 386  
165887 D8QXQ4 PAC:15416559 Selaginella moellendorffii 406  
417268 D8S2N8 PAC:15402310 Selaginella moellendorffii 185  
443492 D8S2N1 PAC:15413964 Selaginella moellendorffii 557  
180500 D8SKD9 PAC:15414005 Selaginella moellendorffii 469  
121095 D8SNA7 PAC:15414757 Selaginella moellendorffii 357  
424158 D8SP04 PAC:15422197 Selaginella moellendorffii 353  
122498 D8SQ69 PAC:15420632 Selaginella moellendorffii 374  
85220 D8R5L6 PAC:15418411 Selaginella moellendorffii 425  
409429 D8RBF3 PAC:15402378 Selaginella moellendorffii 796  
169856 D8RBB7 PAC:15405838 Selaginella moellendorffii 629  
64240 D8QRF4 PAC:15423342 Selaginella moellendorffii 410  
185127 D8T3Q2 PAC:15403086 Selaginella moellendorffii 357  
evm.model.supercontig_1.412 PAC:16404358 Carica papaya 414  
evm.model.supercontig_106.52 PAC:16405218 Carica papaya 372  
evm.model.supercontig_189.4 PAC:16411816 Carica papaya 395  
evm.model.supercontig_36.76 PAC:16418464 Carica papaya 651  
evm.model.supercontig_4.68 PAC:16419365 Carica papaya 564  
evm.model.supercontig_6.187 PAC:16423361 Carica papaya 405  
evm.model.supercontig_66.10 PAC:16424542 Carica papaya 634  
evm.model.supercontig_71.17 PAC:16425423 Carica papaya 292  
29983.m003246 B9RW49 PAC:16815012 Ricinus communis 348  
30074.m001410 B9S747 PAC:16816971 Ricinus communis 630  
30147.m013802 B9RAM8 PAC:16819818 Ricinus communis 563  
30147.m013803 B9RAM9 PAC:16819819 Ricinus communis 478  
30170.m014036 B9R7T9 PAC:16821874 Ricinus communis 630  
30226.m002030 B9REL9 PAC:16824273 Ricinus communis 390  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15317939
            11222759