Protein Domain : IPR014729

Type:  Domain Name:  Rossmann-like alpha/beta/alpha sandwich fold
Description:  This entry represents domains related by a common ancestor that have a Rossmann-like, 3-layer, alpha/beta/alpha sandwich fold. Protein families in which the domain is found include:Nucleotidylyl transferases () such as cytidylyltransferases [], adenylyltransferases [].Class I aminoacyl-tRNA synthetases (catalytic domain), such as tyrosyl-tRNA synthetase () and glutaminyl-tRNA synthetase () [].Pantothenate synthetases () [].ATP sulphurylase (central domain) []N-type ATP pyrophosphatases, such as beta-lactam synthetase () and GMP synthase () [].PP-loop ATPases such as the cell cycle protein MesJ (N-terminal domain) [].Phosphoadenylyl sulphate (PAPS) reductase []Electron transfer flavoprotein (ETFP) subunits, such as the N-terminal domains of the alpha and beta subunits [].Universal stress protein A (UspA) [].Cryptochrome and DNA photolyase []. Short Name:  Rossmann-like_a/b/a_fold
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9 Child Features

DB identifier Type Name
IPR003848 Domain Domain of unknown function DUF218
IPR024951 Domain Sulphate adenylyltransferase catalytic domain
IPR002500 Domain Phosphoadenosine phosphosulphate reductase
IPR006016 Domain UspA
IPR001962 Domain Asparagine synthase
IPR011063 Domain tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal
IPR014730 Domain Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
IPR022310 Domain NAD/GMP synthase
IPR020536 Domain Thil, AANH domain

8 Contains

DB identifier Type Name
IPR002300 Domain Aminoacyl-tRNA synthetase, class Ia
IPR009008 Domain Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
IPR004821 Domain Cytidyltransferase-like domain
IPR015864 Domain FAD synthetase
IPR001412 Conserved_site Aminoacyl-tRNA synthetase, class I, conserved site
IPR000049 Conserved_site Electron transfer flavoprotein, beta-subunit, conserved site
IPR020554 Conserved_site Uncharacterised protein family UPF0021, conserved site
IPR018223 Conserved_site Argininosuccinate synthase, conserved site

1 Cross References

Identifier
G3DSA:3.40.50.620

52 Found Ins

DB identifier Type Name
IPR006426 Family Asparagine synthase, glutamine-hydrolyzing
IPR002307 Family Tyrosine-tRNA ligase
IPR004526 Family Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic
IPR004506 Family tRNA-specific 2-thiouridylase
IPR001278 Family Arginine-tRNA ligase
IPR002301 Family Isoleucine-tRNA ligase
IPR006015 Family Universal stress protein A
IPR002081 Family Cryptochrome/DNA photolyase, class 1
IPR014134 Family Cryptochrome, plant
IPR006050 Domain DNA photolyase, N-terminal
IPR002305 Family Aminoacyl-tRNA synthetase, class Ic
IPR004493 Family Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic
IPR005248 Family Probable nicotinate-nucleotide adenylyltransferase
IPR002761 Domain Diphthamide synthase domain
IPR002306 Family Tryptophan-tRNA ligase
IPR012089 Family 2-thiocytidine tRNA biosynthesis protein, TtcA
IPR001674 Domain GMP synthase, C-terminal
IPR008148 Family DNA photolyase, class 2
IPR020058 Domain Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
IPR004527 Family Glutamate-tRNA ligase, bacterial/mitochondrial
IPR000924 Family Glutamyl/glutaminyl-tRNA synthetase
IPR015803 Family Cysteine-tRNA ligase
IPR012255 Family Electron transfer flavoprotein, beta subunit
IPR003721 Family Pantoate-beta-alanine ligase
IPR002303 Family Valine-tRNA ligase
IPR014133 Family Cryptochrome, DASH
IPR001308 Family Electron transfer flavoprotein, alpha subunit
IPR001518 Family Argininosuccinate synthase
IPR004508 Family Thioredoxin-independent 5'-adenylylsulphate reductase
IPR002302 Family Leucine-tRNA ligase

0 GO Annotation

0 Ontology Annotations

0 Parent Features

48615 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
430219 D8T8Q9 PAC:15418484 Selaginella moellendorffii 447  
231581 D8RGQ6 PAC:15417642 Selaginella moellendorffii 795  
411620 D8RII3 PAC:15410103 Selaginella moellendorffii 345  
412437 D8RLH6 PAC:15411558 Selaginella moellendorffii 160  
438145 D8QUE8 PAC:15418888 Selaginella moellendorffii 664  
69126 D8QVQ4 PAC:15414996 Selaginella moellendorffii 153  
78045 D8QVD0 PAC:15418493 Selaginella moellendorffii 336  
79236 D8QVT5 PAC:15422820 Selaginella moellendorffii 187  
413484 D8RPM2 PAC:15414666 Selaginella moellendorffii 577  
97996 D8RP69 PAC:15414747 Selaginella moellendorffii 457  
413662 D8RPT5 PAC:15416082 Selaginella moellendorffii 282  
413659 D8RPT2 PAC:15416069 Selaginella moellendorffii 238  
58827 D8RQR0 PAC:15410230 Selaginella moellendorffii 124  
232153 D8RRQ6 PAC:15417413 Selaginella moellendorffii 253  
54556 D8RRI5 PAC:15418590 Selaginella moellendorffii 337  
99947 D8RR46 PAC:15420385 Selaginella moellendorffii 224  
173688 D8RRZ9 PAC:15416396 Selaginella moellendorffii 194  
267677 D8RRV6 PAC:15412861 Selaginella moellendorffii 159  
56433 D8RVA9 PAC:15423516 Selaginella moellendorffii 190  
58615 D8RX19 PAC:15408565 Selaginella moellendorffii 152  
443018 D8RXS4 PAC:15410647 Selaginella moellendorffii 215  
166255 D8QWX6 PAC:15414937 Selaginella moellendorffii 699  
80221 D8QY71 PAC:15403706 Selaginella moellendorffii 797  
267968 D8RZ09 PAC:15415155 Selaginella moellendorffii 731  
417072 D8S199 PAC:15423039 Selaginella moellendorffii 166  
50946 D8S5B0 PAC:15409921 Selaginella moellendorffii 775  
271357 PAC:15422403 Selaginella moellendorffii 146  
81509 D8QYR0 PAC:15408916 Selaginella moellendorffii 582  
58286 D8S985 PAC:15405662 Selaginella moellendorffii 163  
420051 D8SAD9 PAC:15409849 Selaginella moellendorffii 206  

11 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8962055
            8548458
            9261082
            16344011
            15894617
            14684898
            7701318
            16460002
            16387658
            16952944
            17101984