Protein Domain : IPR005821

Type:  Domain Name:  Ion transport domain
Description:  This domain is found in sodium, potassium, and calcium ion channels proteins. The proteins have 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some Na channel proteins the domain is repeated four times, whereas in others (e.g. K channels) the protein forms a tetramer in the membrane. A bacterial structure of the protein is known for the last two helices but is not included in the Pfam family due to it lacking the first four helices. Short Name:  Ion_trans_dom
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0 Child Features

0 Contains

1 Cross References

Identifier
PF00520

40 Found Ins

DB identifier Type Name
IPR003938 Family Potassium channel, voltage-dependent, EAG/ELK/ERG
IPR003091 Family Potassium channel
IPR002077 Family Voltage-dependent calcium channel, alpha-1 subunit
IPR003968 Family Potassium channel, voltage dependent, Kv
IPR015925 Family Ryanodine receptor-related
IPR005404 Family Potassium channel, voltage dependent, Kv3.3
IPR003967 Family Potassium channel, voltage-dependent, ERG
IPR003949 Family Potassium channel, voltage-dependent, EAG
IPR003950 Family Potassium channel, voltage-dependent, ELK
IPR013333 Family Ryanodine receptor
IPR000493 Family Inositol 1,4,5-trisphosphate-binding protein receptor
IPR004049 Family Potassium channel, voltage dependent, Kv1.2
IPR003972 Family Potassium channel, voltage dependent, Kv1
IPR004048 Family Potassium channel, voltage dependent, Kv1.1
IPR003975 Family Potassium channel, voltage dependent, Kv4
IPR004055 Family Potassium channel, voltage dependent, Kv4.2
IPR004052 Family Potassium channel, voltage dependent, Kv1.5
IPR004053 Family Potassium channel, voltage dependent, Kv1.6
IPR004050 Family Potassium channel, voltage dependent, Kv1.3
IPR003937 Family Potassium channel, voltage dependent, KCNQ
IPR003973 Family Potassium channel, voltage dependent, Kv2
IPR004729 Family Transient receptor potential channel
IPR005460 Family Transient receptor potential channel, canonical 4
IPR008348 Family Transient receptor potential channel, vanilloid 4
IPR005458 Family Transient receptor potential channel, canonical 2
IPR005461 Family Transient receptor potential channel, canonical 5
IPR005462 Family Transient receptor potential channel, canonical 6
IPR005449 Family Voltage-dependent calcium channel, R-type, alpha-1 subunit
IPR001696 Family Voltage gated sodium channel, alpha subunit
IPR008052 Family Voltage gated sodium channel, alpha-4 subunit, mammalian

4 GO Annotations

GO Term Gene Name
GO:0005216 IPR005821
GO:0006811 IPR005821
GO:0055085 IPR005821
GO:0016020 IPR005821

4 Ontology Annotations

GO Term Gene Name
GO:0005216 IPR005821
GO:0006811 IPR005821
GO:0055085 IPR005821
GO:0016020 IPR005821

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
416791 D8S0F3 PAC:15403235 Selaginella moellendorffii 758  
266723 D8QYM9 PAC:15410630 Selaginella moellendorffii 670  
113786 D8SCK7 PAC:15418666 Selaginella moellendorffii 726  
84488 D8R498 PAC:15417160 Selaginella moellendorffii 685  
266514 D8QPN0 PAC:15408982 Selaginella moellendorffii 632  
426835 D8SXN1 PAC:15411213 Selaginella moellendorffii 196  
89324 D8RB40 PAC:15408478 Selaginella moellendorffii 663  
evm.TU.contig_35659.1 PAC:16430690 Carica papaya 353  
evm.TU.contig_39659.1 PAC:16431365 Carica papaya 148  
evm.model.supercontig_12.38 PAC:16406876 Carica papaya 698  
evm.model.supercontig_124.35 PAC:16407192 Carica papaya 545  
evm.model.supercontig_14.141 PAC:16408638 Carica papaya 712  
evm.model.supercontig_14.142 PAC:16408639 Carica papaya 702  
evm.model.supercontig_140.41 PAC:16408887 Carica papaya 702  
evm.model.supercontig_205.30 PAC:16413251 Carica papaya 183  
evm.model.supercontig_205.27 PAC:16413247 Carica papaya 144  
evm.model.supercontig_23.37 PAC:16414246 Carica papaya 683  
evm.model.supercontig_3.357 PAC:16416654 Carica papaya 825  
evm.model.supercontig_3.60 PAC:16416845 Carica papaya 707  
evm.model.supercontig_30.2 PAC:16416966 Carica papaya 727  
evm.model.supercontig_46.159 PAC:16420443 Carica papaya 590  
evm.model.supercontig_65.6 PAC:16424470 Carica papaya 716  
evm.model.supercontig_75.8 PAC:16425922 Carica papaya 466  
evm.model.supercontig_848.1 PAC:16427405 Carica papaya 612  
evm.model.supercontig_92.107 PAC:16428564 Carica papaya 702  
29742.m001433 B9SBJ2 PAC:16807664 Ricinus communis 630  
29822.m003360 B9RUB3 PAC:16809730 Ricinus communis 654  
29848.m004476 B9RNP6 PAC:16811133 Ricinus communis 629  
29983.m003189 B9RVZ4 PAC:16814957 Ricinus communis 395  
29983.m003190 B9RVZ5 PAC:16814958 Ricinus communis 743  

0 Publications