Protein Domain : IPR001041

Type:  Domain Name:  2Fe-2S ferredoxin-type iron-sulfur binding domain
Description:  Ferredoxins are small, acidic, electron transfer proteins that are ubiquitous in biological redox systems. They have either 4Fe-4S, 3Fe-4S, or 2Fe-2Scluster. Among them, ferredoxin with one 2Fe-2S cluster per molecule are present in plants, animals, and bacteria, and form a distinct Ferredoxinfamily []. They are proteins of around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated. This conserved region is also found as a domain in various metabolic enzymes.Several structures of the 2Fe-2S ferredoxin-type domain have been determined []. The domain is classified as a beta-grasp, which is characterised as having a beta-sheet comprised of four beta-strands and one alpha-helix flanking the sheet. The two Fe atoms are coordinated tetrahedrally by the two inorganic S atoms and four cysteinyl S atoms. Short Name:  2Fe-2S_ferredoxin-type
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1 Child Features

DB identifier Type Name
IPR025192 Domain Succinate dehydogenase/fumarate reductase N-terminal

4 Contains

DB identifier Type Name
IPR019574 Domain NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
IPR006058 Binding_site 2Fe-2S ferredoxin, iron-sulphur binding site
IPR000283 Conserved_site NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
IPR018298 Binding_site Adrenodoxin, iron-sulphur binding site

3 Cross Referencess

Identifier
PF00111
PS51085
SSF54292

15 Found Ins

DB identifier Type Name
IPR010228 Family NADH:ubiquinone oxidoreductase, subunit G
IPR001055 Family Adrenodoxin
IPR001221 Family Phenol hydroxylase reductase
IPR016208 Family Aldehyde oxidase/xanthine dehydrogenase
IPR004489 Family Succinate dehydrogenase/fumarate reductase iron-sulphur protein
IPR000951 Family Phthalate dioxygenase reductase
IPR014307 Domain Xanthine dehydrogenase, small subunit
IPR012175 Family Xanthine dehydrogenase, small subunit, bacteria
IPR014313 Family Aldehyde oxidase
IPR016214 Family NAD-reducing hydrogenase, HoxS gamma subunit
IPR017606 Family 4-hydroxybenzoyl-CoA reductase, gamma subunit
IPR017611 Family Xanthine dehydrogenase E subunit
IPR017697 Family Selenium-dependent xanthine dehydrogenase
IPR010205 Family Na(+)-translocating NADH-quinone reductase subunit F
IPR011884 Family Phenylacetate-CoA oxygenase/reductase, PaaK subunit

2 GO Annotations

GO Term Gene Name
GO:0009055 IPR001041
GO:0051536 IPR001041

2 Ontology Annotations

GO Term Gene Name
GO:0009055 IPR001041
GO:0051536 IPR001041

1 Parent Features

DB identifier Type Name
IPR012675 Domain Beta-grasp domain

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
236581 D8TAU0 PAC:15409908 Selaginella moellendorffii 97  
96875 D8RLG8 PAC:15410972 Selaginella moellendorffii 1334  
59108 D8RMP1 PAC:15407586 Selaginella moellendorffii 126  
140989 D8QU22 PAC:15410714 Selaginella moellendorffii 126  
230127 D8QV66 PAC:15411540 Selaginella moellendorffii 97  
59158 D8RPW7 PAC:15407711 Selaginella moellendorffii 104  
443347 D8S0L6 PAC:15412996 Selaginella moellendorffii 1285  
268099 D8S343 PAC:15411279 Selaginella moellendorffii 1336  
108358 D8S3V0 PAC:15422830 Selaginella moellendorffii 217  
166487 D8QYW7 PAC:15416437 Selaginella moellendorffii 146  
444239 D8S844 PAC:15415133 Selaginella moellendorffii 1326  
57580 D8S953 PAC:15405008 Selaginella moellendorffii 234  
82638 D8R0V1 PAC:15412741 Selaginella moellendorffii 258  
118126 D8SIL6 PAC:15406153 Selaginella moellendorffii 248  
38551 D8R341 PAC:15415927 Selaginella moellendorffii 101  
230918 D8R574 PAC:15417620 Selaginella moellendorffii 98  
85593 D8R553 PAC:15420861 Selaginella moellendorffii 248  
86191 D8R556 PAC:15420709 Selaginella moellendorffii 248  
229827 D8QPI9 PAC:15413724 Selaginella moellendorffii 97  
159119 D8SX90 PAC:15415641 Selaginella moellendorffii 691  
89261 D8RBK4 PAC:15407766 Selaginella moellendorffii 136  
69317 D8RAV5 PAC:15416420 Selaginella moellendorffii 104  
evm.model.supercontig_103.92 PAC:16404982 Carica papaya 1364  
evm.model.supercontig_103.94 PAC:16404984 Carica papaya 57  
evm.model.supercontig_103.95 PAC:16404985 Carica papaya 1301  
evm.model.supercontig_116.77 PAC:16406337 Carica papaya 745  
evm.model.supercontig_118.34 PAC:16406492 Carica papaya 146  
evm.model.supercontig_130.56 PAC:16407962 Carica papaya 281  
evm.model.supercontig_1385.1 PAC:16408502 Carica papaya 70  
evm.model.supercontig_19.250 PAC:16411995 Carica papaya 199  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2065785
            8586613