4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR000283 |
| GO:0042773 | IPR000283 |
| GO:0055114 | IPR000283 |
| GO:0016020 | IPR000283 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR000283 |
| GO:0042773 | IPR000283 |
| GO:0055114 | IPR000283 |
| GO:0016020 | IPR000283 |
| Type: | Conserved_site | Name: | NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site |
| Description: | NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry represents the 75 kDa subunit from NADH:ubiquinone oxidoreductase. Among the many polypeptide subunits that make up complex I, there is one with a molecular weight of 75 kDa (in mammals), which is the largest subunit of complex I and is a component of the iron-sulphur (IP) fragment of the enzyme. It seems to bind to two 4Fe-4S clusters (called N-3 and N-4). | Short Name: | NADH_UbQ_OxRdtase_75kDa_su_CS |
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR000283 |
| GO:0042773 | IPR000283 |
| GO:0055114 | IPR000283 |
| GO:0016020 | IPR000283 |
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR000283 |
| GO:0042773 | IPR000283 |
| GO:0055114 | IPR000283 |
| GO:0016020 | IPR000283 |
