1 Contains
| DB identifier | Type | Name |
|---|---|---|
| IPR000283 | Conserved_site | NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site |
| Type: | Domain | Name: | NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding |
| Description: | NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry describes the G subunit (one of 14 subunits, A to N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria while translocating protons, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This family does not contain related subunits from formate dehydrogenase complexes.This entry represents the iron-sulphur binding domain of the G subunit. | Short Name: | NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd |
| DB identifier | Type | Name |
|---|---|---|
| IPR000283 | Conserved_site | NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site |
