| Type: | Family | Name: | Selenium-dependent xanthine dehydrogenase |
| Description: | Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum [, ]. | Short Name: | Xdh |
| DB identifier | Type | Name |
|---|---|---|
| IPR001041 | Domain | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
| IPR002888 | Domain | [2Fe-2S]-binding |
| IPR008274 | Domain | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding |
| IPR000674 | Domain | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead |
| IPR006058 | Binding_site | 2Fe-2S ferredoxin, iron-sulphur binding site |
