Protein Domain : IPR005740

Type:  Family Name:  DNA topoisomerase 4 subunit B, Gram-positive
Description:  This entry represents subunit B (parE) of topoisomerase IV from Gram positive bacteria. Topoisomerase IV primarily decatenates DNA and relaxes positive supercoils, which is important in bacteria, where the circular chromosome becomes catenated, or linked, during replication []. Topoisomerase IV consists of two polypeptide subunits, parC (subunit A), which is homologous to gyrA of topoisomerase II, and parE (subunit B), which is homologous to gyrB of topoisomerase II. Short Name:  ParE
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0 Child Features

8 Contains

DB identifier Type Name
IPR003594 Domain Histidine kinase-like ATPase, C-terminal domain
IPR020568 Domain Ribosomal protein S5 domain 2-type fold
IPR006171 Domain Toprim domain
IPR013760 Domain DNA topoisomerase, type IIA-like domain
IPR013506 Domain DNA topoisomerase, type IIA, subunit B, domain 2
IPR013759 Domain DNA topoisomerase, type IIA, central domain
IPR002288 Domain DNA gyrase B subunit, C-terminal
IPR018522 Conserved_site DNA topoisomerase, type IIA, conserved site

2 Cross Referencess

Identifier
TIGR01058
MF_00939

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0003677 IPR005740
GO:0003918 IPR005740
GO:0005524 IPR005740
GO:0006265 IPR005740
GO:0005694 IPR005740

5 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR005740
GO:0003918 IPR005740
GO:0005524 IPR005740
GO:0006265 IPR005740
GO:0005694 IPR005740

1 Parent Features

DB identifier Type Name
IPR000565 Family DNA topoisomerase, type IIA, subunit B

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16023670