Protein Domain : IPR007110

Type:  Domain Name:  Immunoglobulin-like domain
Description:  The basic structure of immunoglobulin (Ig) molecules is a tetramer of two light chains and two heavy chains linked by disulphide bonds. There are two types of light chains: kappa and lambda, each composed of a constant domain (CL) and a variable domain (VL). There are five types of heavy chains: alpha, delta, epsilon, gamma and mu, all consisting of a variable domain (VH) and three (in alpha, delta and gamma) or four (in epsilon and mu) constant domains (CH1 to CH4). Ig molecules are highly modular proteins, in which the variable and constant domains have clear, conserved sequence patterns. The domains in Ig and Ig-like molecules are grouped into four types: V-set (variable; ), C1-set (constant-1; ), C2-set (constant-2; ) and I-set (intermediate; ) []. Structural studies have shown that these domains share a common core Greek-key beta-sandwich structure, with the types differing in the number of strands in the beta-sheets as well as in their sequence patterns [, ].Immunoglobulin-like domains that are related in both sequence and structure can be found in several diverse protein families. Ig-like domains are involved in a variety of functions, including cell-cell recognition, cell-surface receptors, muscle structure and the immune system []. Short Name:  Ig-like_dom
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1 Child Features

DB identifier Type Name
IPR003597 Domain Immunoglobulin C1-set

6 Contains

DB identifier Type Name
IPR003599 Domain Immunoglobulin subtype
IPR013098 Domain Immunoglobulin I-set
IPR003598 Domain Immunoglobulin subtype 2
IPR013151 Domain Immunoglobulin
IPR003006 Conserved_site Immunoglobulin/major histocompatibility complex, conserved site
IPR013162 Domain CD80-like, immunoglobulin C2-set

2 Cross Referencess

Identifier
PS50835
SSF48726

37 Found Ins

DB identifier Type Name
IPR016243 Family Tyrosine-protein kinase, CSF-1/PDGF receptor family
IPR004076 Family Interleukin-1 receptor type 1
IPR004074 Family Interleukin-1 receptor type I/II
IPR004077 Family Interleukin-1 receptor type II
IPR004078 Family Interleukin-1 binding protein
IPR015621 Family Interleukin-1 receptor family
IPR006704 Family Leukocyte surface antigen CD47
IPR016332 Family Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor
IPR016248 Family Fibroblast growth factor receptor family
IPR015513 Family Semaphorin 3E
IPR016247 Family Tyrosine-protein kinase, receptor ROR
IPR018250 Family Neuregulin-1
IPR016663 Family Myelin-oligodendrocyte glycoprotein
IPR020461 Family Tyrosine-protein kinase, neurotrophic receptor, type 1
IPR020446 Family Tyrosine-protein kinase, neurotrophic receptor, type 3
IPR020455 Family Tyrosine-protein kinase, neurotrophic receptor, type 2
IPR020777 Family Tyrosine-protein kinase, neurotrophic receptor
IPR011390 Family Insulin-like growth factor binding protein-related protein (IGFBP-rP), MAC25
IPR020675 Family Myosin light chain kinase-related
IPR020682 Family Obscurin-myosin light chain kinase
IPR015725 Family Telokin/Myosin light chain kinase
IPR015726 Family Serine/threonine protein kinase, striated muscle-specific
IPR015631 Family Signalling lymphocyte activation molecule family receptors
IPR009136 Family Vascular endothelial growth factor receptor 2 (VEGFR2)
IPR009135 Family Vascular endothelial growth factor receptor 1 (VEGFR1)
IPR009137 Family Vascular endothelial growth factor receptor 3 (VEGFR3)
IPR009151 Family Basigin
IPR000973 Family T-cell surface antigen CD4
IPR000920 Family Myelin P0 protein-related
IPR001038 Family Glycoprotein C/ glycoprotein A

1 GO Annotation

GO Term Gene Name
GO:0005515 IPR007110

1 Ontology Annotations

GO Term Gene Name
GO:0005515 IPR007110

1 Parent Features

DB identifier Type Name
IPR013783 Domain Immunoglobulin-like fold

770 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
30014.m000437 B9SSA1 PAC:16815658 Ricinus communis 465  
48361.m000023 B9TKV2 PAC:16828081 Ricinus communis 176  
50636.m000013 B9TMA9 PAC:16828290 Ricinus communis 137  
Cucsa.042080.1 A0A0A0L637 PAC:16952871 Cucumis sativus 391  
AT5G48740.1 C0LGV0 PAC:19667930 Arabidopsis thaliana 895  
AT3G46280.1 Q8GYH9 PAC:19662369 Arabidopsis thaliana 471  
AT3G55665.1 A8MR68 PAC:19664104 Arabidopsis thaliana 168  
AT2G23770.1 O64825 PAC:19640620 Arabidopsis thaliana 612  
Thhalv10016208m V4MJD0 PAC:20180427 Eutrema salsugineum 912  
Thhalv10005431m V4KXE5 PAC:20198940 Eutrema salsugineum 82  
Lus10003063 PAC:23154542 Linum usitatissimum 686  
Potri.007G094800.1 B9HFF1 PAC:27016515 Populus trichocarpa 307  
Potri.013G030100.1 A0A2K1Y0A2 PAC:26994485 Populus trichocarpa 564  
Potri.013G030700.1 U7DTC9 PAC:26995046 Populus trichocarpa 305  
Potri.010G197700.4 A0A2K1YWZ4 PAC:26979058 Populus trichocarpa 751  
Potri.010G197700.1 PAC:26979057 Populus trichocarpa 794  
Gorai.001G186800.5 A0A0D2PTI3 PAC:26820186 Gossypium raimondii 812  
Gorai.001G186800.6 A0A0D2QSF4 PAC:26820187 Gossypium raimondii 804  
Gorai.001G186800.7 A0A0D2QSF4 PAC:26820188 Gossypium raimondii 804  
Gorai.001G186800.8 A0A0D2QSF4 PAC:26820189 Gossypium raimondii 804  
Gorai.001G186800.2 A0A0D2NB92 PAC:26820183 Gossypium raimondii 905  
Gorai.001G186800.3 A0A0D2PTI7 PAC:26820184 Gossypium raimondii 885  
Gorai.001G186800.4 A0A0D2Q0R9 PAC:26820185 Gossypium raimondii 841  
Gorai.001G186800.1 A0A0D2NB97 PAC:26820182 Gossypium raimondii 909  
Gorai.003G187200.1 A0A0D2QVK8 PAC:26798052 Gossypium raimondii 312  
Gorai.003G187200.4 A0A0D2P3K1 PAC:26798055 Gossypium raimondii 204  
Gorai.003G187200.3 A0A0D2QN53 PAC:26798054 Gossypium raimondii 233  
Gorai.003G187200.2 A0A0D2MQT3 PAC:26798053 Gossypium raimondii 290  
Gorai.004G225900.1 A0A0D2S494 PAC:26777766 Gossypium raimondii 909  
Gorai.012G098100.1 A0A0D2VXM0 PAC:26826347 Gossypium raimondii 72  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11377196
            9417933
            15327963
            10698639