| Type: | Family | Name: | Leukocyte surface antigen CD47 |
| Description: | Leukocyte surface antigen CD47 (also known as integrin-associated protein, IAP) is a widely expressed membrane protein with multiple functions in immunological and neuronal processes. For example, CD47-induces caspase-independent cell death which may be mediated by cytoskeleton reorganisation []. In red blood cells, CD47 acts like a marker of self by ligating the macrophage inhibitory receptor signal regulatory protein alpha []. The protein can also act as a thrombospondin receptor [].This pattern also recognises a group of CD-47-like proteins found in poxviruses (Poxviridae). | Short Name: | CD47 |
