Protein Domain : IPR015699

Type:  Family Name:  DNA-directed RNA pol I, largest subunit
Description:  DNA-dependent RNA polymerases () are responsible for the polymerisation of ribonucleotides into a sequence complementary to the template DNA. In eukaryotes, there are three different forms of DNA-dependent RNA polymerases transcribing different sets of genes. Most RNA polymerases are multimeric enzymes and are composed of a variable number of subunits. RNA synthesis follows after the attachment of RNA polymerase to a specific site, the promoter, on the template DNA strand. The RNA synthesis process continues until a termination sequence is reached. The RNA product, which is synthesised in the 5' to 3' direction, is known as the primary transcript.Eukaryotic nuclei contain three distinct types of RNA polymerases that differ in the RNA they synthesise:1. RNA polymerase I: located in the nucleoli, synthesises precursors of most ribosomal RNAs.2. RNA polymerase II: occurs in the nucleoplasm, synthesises mRNA precursors.3. RNA polymerase III: also occurs in the nucleoplasm, synthesises the precursors of 5S ribosomal RNA, the tRNAs, and a variety of other small nuclear and cytosolic RNAs.Eukaryotic cells are also known to contain separate mitochondrial and chloroplast RNA polymerases. Eukaryotic RNA polymerases, whose molecular masses vary in size from 500 to 700 kDa, contain two non-identical large (greater than 100 kDa) subunits and an array of up to 12 different small (less than 50 kDa) subunits.This entry appears to be specific to RNA polymerase I, largest subunit. Short Name:  DNA-dir_RNA_pol1_lsu
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0 Child Features

6 Contains

DB identifier Type Name
IPR007083 Domain RNA polymerase Rpb1, domain 4
IPR007066 Domain RNA polymerase Rpb1, domain 3
IPR007081 Domain RNA polymerase Rpb1, domain 5
IPR000722 Domain RNA polymerase, alpha subunit
IPR006592 Domain RNA polymerase, N-terminal
IPR007080 Domain RNA polymerase Rpb1, domain 1

1 Cross References

Identifier
PTHR19376:SF11

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003899 IPR015699
GO:0008270 IPR015699
GO:0006351 IPR015699
GO:0005634 IPR015699

4 Ontology Annotations

GO Term Gene Name
GO:0003899 IPR015699
GO:0008270 IPR015699
GO:0006351 IPR015699
GO:0005634 IPR015699

0 Parent Features

682 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
438401 D8QXR6 PAC:15420992 Selaginella moellendorffii 1588  
evm.model.supercontig_92.5 PAC:16428620 Carica papaya 268  
evm.model.supercontig_92.6 PAC:16428631 Carica papaya 938  
evm.model.supercontig_92.7 PAC:16428642 Carica papaya 541  
27810.m000650 B9SL65 PAC:16799255 Ricinus communis 1686  
Cucsa.336830.1 PAC:16978509 Cucumis sativus 1662  
orange1.1g046825m PAC:18128003 Citrus sinensis 1208  
AT3G57660.1 Q9SVY0 PAC:19660190 Arabidopsis thaliana 1670  
Thhalv10005738m V4NE24 PAC:20190645 Eutrema salsugineum 1697  
Ciclev10004132m V4U642 PAC:20789533 Citrus clementina 1715  
Lus10040493 PAC:23174169 Linum usitatissimum 1674  
Lus10011299 PAC:23149929 Linum usitatissimum 1667  
Potri.006G055300.1 PAC:27006156 Populus trichocarpa 1695  
Gorai.003G089300.1 A0A0D2QHR9 PAC:26797805 Gossypium raimondii 1674  
Gorai.006G236800.1 A0A0D2QFT1 PAC:26829171 Gossypium raimondii 242  
30489 I0YR41 PAC:27387830 Coccomyxa subellipsoidea C-169 1671  
36623 C1N756 PAC:27348540 Micromonas pusilla CCMP1545 1665  
65110 C1EFA8 PAC:27402641 Micromonas sp RCC299 1616  
43496 A4SAV6 PAC:27420150 Ostreococcus lucimarinus 1663  
Thecc1EG024782t3 A0A061EY47 PAC:27422811 Theobroma cacao 1400  
Thecc1EG024782t1 A0A061EW90 PAC:27422810 Theobroma cacao 1665  
Thecc1EG024782t2 A0A061EX26 PAC:27422809 Theobroma cacao 1689  
Thecc1EG024782t4 A0A061EXG4 PAC:27422812 Theobroma cacao 1397  
Migut.J01785.1.p A0A022RI56 PAC:28942276 Mimulus guttatus 1719  
Araha.1744s0002.1.p PAC:28861045 Arabidopsis halleri 1665  
Cagra.0210s0003.1.p PAC:28908205 Capsella grandiflora 1651  
Glyma.10G095200.1.p I1L9X1 PAC:30477020 Glycine max 1651  
Glyma.02G181200.2.p A0A0R0KYG7 PAC:30511094 Glycine max 941  
Glyma.02G181200.1.p A0A0R0L5S8 PAC:30511093 Glycine max 1288  
Brara.G01751.1.p A0A397YLY9 PAC:30632040 Brassica rapa FPsc 821  

0 Publications