| Type: | Domain | Name: | RNA polymerase, N-terminal |
| Description: | The task of transcribing nuclear genes is shared between three RNA polymerases in eukaryotes: RNA polymerase (pol) I synthesizes the large rRNA, pol II synthesizes mRNA and pol III synthesizes tRNA and 5S rRNA []. Pol I transcription is localised to discrete sites called nucleoli; these can be likened to ribosomefactories, in which rRNA is synthesised by pol I in the fibrillar centres and then processed and assembled into ribosomes in the surrounding granular regions []. Prokaryotes, in contrast, posses a single RNA polymerase, with transcription being controlled by the particular signam factor interacting with the catalytic core.This entry describes an N-terminal conserved region which can be found in the largest subunits of prokaryoptic and eukaryotic RNA polymerases. | Short Name: | RNA_pol_N |
| DB identifier | Type | Name |
|---|---|---|
| IPR015699 | Family | DNA-directed RNA pol I, largest subunit |
| IPR012754 | Family | DNA-directed RNA polymerase, subunit beta-prime |
| IPR015700 | Family | DNA-directed RNA polymerase III subunit RPC1 |
| IPR012755 | Family | DNA-directed RNA polymerase, subunit gamma |
| IPR012758 | Family | DNA-directed RNA polymerase subunit A' (Rpo1N) |
| GO Term | Gene Name |
|---|---|
| GO:0003677 | IPR006592 |
| GO:0003899 | IPR006592 |
| GO:0006351 | IPR006592 |
