Protein Domain : IPR013325

Type:  Domain Name:  RNA polymerase sigma factor, region 2
Description:  The bacterial core RNA polymerase complex, which consists of five subunits, is sufficient for transcription elongation and termination but is unable to initiate transcription. Transcription initiation from promoter elements requires a sixth, dissociable subunit called a sigma factor, which reversibly associates with the core RNA polymerase complex to form a holoenzyme []. RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma factors. Two of these factors, Sigma70 (gene rpoD; major sigma factor) and Sigma54 (gene rpoN or ntrA) direct the transcription of a wide variety of genes. The other sigma factors, known as alternative sigma factors, are required for the transcription of specific subsets of genes.This entry represents region 2 (sigma2 domain) found in several sigma factors, often in conjunction with sigma3 and sigma4 domains (). This region is present in Sigma70 [], Sigma28 (FliA), SigA [], SigR and RpoE. The sigma2 domain has a conserved 4-helical core, and often a variable insert subdomain. Short Name:  RNA_pol_sigma_r2
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0 Child Features

4 Contains

DB identifier Type Name
IPR007627 Domain RNA polymerase sigma-70 region 2
IPR009042 Domain RNA polymerase sigma-70 region 1.2
IPR007631 Domain RNA polymerase sigma factor 70, non-essential domain
IPR000838 Conserved_site RNA polymerase sigma factor 70, ECF, conserved site

1 Cross References

Identifier
SSF88946

32 Found Ins

DB identifier Type Name
IPR014284 Domain RNA polymerase sigma-70 like domain
IPR000943 Domain RNA polymerase sigma-70
IPR016262 Family RNA polymerase sigma factor, SigB/C/D/F, plastid
IPR012759 Family RNA polymerase sigma factor RpoH, proteobacteria
IPR016263 Family RNA polymerase sporulation-specific sigma factor
IPR017848 Family RNA polymerase sigma factor, RpoD-like, cyanobacteria
IPR014209 Family RNA polymerase sigma-K type
IPR012761 Family RNA polymerase sigma factor RpoS
IPR016371 Family RNA polymerase sigma-H factor
IPR014218 Family RNA polymerase sigma-H type
IPR014200 Family RNA polymerase sigma-E type
IPR012845 Family RNA polymerase sigma factor, FliA/WhiG
IPR014305 Family RNA polymerase sigma-G type, actinobacteria
IPR014327 Family RNA polymerase sigma-70, Bacteroidetes type
IPR014325 Family RNA polymerase sigma-E factor, actinobacteria
IPR014326 Family RNA polymerase sigma-70 factor, Planctomycetaceae
IPR014322 Family RNA polymerase sigma-B/F/G type
IPR014236 Family RNA polymerase sigma-F type
IPR014288 Family RNA polymerase sigma-B factor
IPR014212 Family RNA polymerase sigma-G type
IPR014331 Family RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica
IPR014303 Family RNA polymerase sigma-70, ECF type
IPR014304 Family RNA polymerase sigma-Z type
IPR014300 Family RNA polymerase sigma-V type
IPR014244 Family RNA polymerase sigma-I type
IPR011517 Family RNA polymerase sigma-70 ECF-like
IPR014286 Family RNA polymerase sigma-70 RpoE type
IPR014293 Family RNA polymerase sigma-70, actinobacteria
IPR014294 Family RNA polymerase sigma-W, bacillaceae
IPR014289 Family RNA polymerase sigma-24-related

5 GO Annotations

GO Term Gene Name
GO:0003677 IPR013325
GO:0003700 IPR013325
GO:0016987 IPR013325
GO:0006352 IPR013325
GO:0006355 IPR013325

5 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR013325
GO:0003700 IPR013325
GO:0016987 IPR013325
GO:0006352 IPR013325
GO:0006355 IPR013325

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
147096 D8RGX1 PAC:15401952 Selaginella moellendorffii 458  
53596 D8S3G8 PAC:15415781 Selaginella moellendorffii 326  
117159 D8SHL6 PAC:15403291 Selaginella moellendorffii 292  
266972 D8R5F3 PAC:15412233 Selaginella moellendorffii 249  
evm.model.supercontig_125.39 PAC:16407269 Carica papaya 443  
evm.model.supercontig_3.54 PAC:16416838 Carica papaya 547  
evm.model.supercontig_3807.1 PAC:16418945 Carica papaya 333  
evm.model.supercontig_56.16 PAC:16422721 Carica papaya 564  
evm.model.supercontig_73.29 PAC:16425606 Carica papaya 357  
29794.m003368 B9RRX0 PAC:16808728 Ricinus communis 560  
29864.m001444 B9RVK0 PAC:16811756 Ricinus communis 389  
30078.m002307 B9S0J0 PAC:16817418 Ricinus communis 548  
30148.m001412 B9SDA3 PAC:16820557 Ricinus communis 569  
30148.m001468 B9SDF8 PAC:16820612 Ricinus communis 508  
30169.m006532 B9RIL8 PAC:16821332 Ricinus communis 501  
30445.m000022 B9THE0 PAC:16824427 Ricinus communis 315  
30892.m000027 B9TKG6 PAC:16824679 Ricinus communis 190  
32775.m000024 B9TEC6 PAC:16825552 Ricinus communis 271  
33001.m000032 PAC:16825645 Ricinus communis 122  
34613.m000038 B9TJU4 PAC:16826284 Ricinus communis 139  
43220.m000021 B9TQM5 PAC:16827580 Ricinus communis 122  
47514.m000023 B9TMI4 PAC:16828001 Ricinus communis 172  
47961.m000024 PAC:16828045 Ricinus communis 141  
28920.m000046 PAC:16801985 Ricinus communis 169  
Cucsa.362600.1 A0A0A0K917 PAC:16980950 Cucumis sativus 580  
Cucsa.363080.1 PAC:16981024 Cucumis sativus 667  
Cucsa.012950.1 PAC:16951584 Cucumis sativus 585  
Cucsa.012950.2 A0A0A0LCQ9 PAC:16951585 Cucumis sativus 547  
Cucsa.124610.1 A0A0A0KEQ6 PAC:16961743 Cucumis sativus 562  
Cucsa.073340.2 PAC:16955602 Cucumis sativus 473  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            3052291
            11931761
            8858155