Protein Domain : IPR000014

Type:  Domain Name:  PAS domain
Description:  PAS domains are involved in many signalling proteins where they are used as a signal sensor domain []. PAS domains appear in archaea,bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Haeme,flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. The PAS domain was named after three proteins that itoccurs in: Per- period circadian proteinArnt- Ah receptor nuclear translocator proteinSim- single-minded protein.PAS domains are often associated with PAC domains . It appears that these domains are directly linked, and that together they form the conserved 3D PAS fold. The division between the PAS and PAC domains is caused by major differences in sequences in the region connecting these two motifs []. In human PAS kinase, this region has been shown to be very flexible, and adopts different conformations depending on the bound ligand [].Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels []. Short Name:  PAS
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3 Child Features

DB identifier Type Name
IPR013767 Domain PAS fold
IPR013655 Domain PAS fold-3
IPR013656 Domain PAS fold-4

0 Contains

6 Cross Referencess

Identifier
PF13188
PF13426
PS50112
SM00091
TIGR00229
SSF55785

13 Found Ins

DB identifier Type Name
IPR012129 Family Phytochrome A/B/C/D/E
IPR001294 Family Phytochrome
IPR014310 Family Signal transduction histidine kinase, phosphate regulon sensor PhoR
IPR003949 Family Potassium channel, voltage-dependent, EAG
IPR003950 Family Potassium channel, voltage-dependent, ELK
IPR014409 Family Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB
IPR017181 Family Signal transduction histidine kinase, CHASE2/PAS sensor domain-containing, predicted
IPR017232 Family Signal transduction histidine kinase, nitrogen fixation and metabolism regulator
IPR014285 Family Nitrogen fixation negative regulator NifL
IPR011785 Family Transcription regulator PpsR
IPR012704 Family Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR
IPR012130 Family Photoactive yellow-protein
IPR015524 Family Period circadian protein 3

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
172224 D8RKK4 PAC:15410332 Selaginella moellendorffii 930  
270954 Q0Q432 PAC:15401824 Selaginella moellendorffii 840  
174189 D8RTR5 PAC:15415582 Selaginella moellendorffii 587  
405045 PAC:15410073 Selaginella moellendorffii 1067  
443359 D8S0P0 PAC:15413036 Selaginella moellendorffii 394  
230655 D8R388 PAC:15415465 Selaginella moellendorffii 952  
20385 PAC:15406107 Selaginella moellendorffii 792  
161430 D8T691 PAC:15401681 Selaginella moellendorffii 1143  
evm.TU.contig_34279.1 PAC:16430431 Carica papaya 257  
evm.model.supercontig_136.26 PAC:16408315 Carica papaya 286  
evm.model.supercontig_139.19 PAC:16408515 Carica papaya 1007  
evm.model.supercontig_17.112 PAC:16410603 Carica papaya 1112  
evm.model.supercontig_23.44 PAC:16414254 Carica papaya 531  
evm.model.supercontig_232.11 PAC:16414344 Carica papaya 382  
evm.model.supercontig_48.231 PAC:16420875 Carica papaya 986  
evm.model.supercontig_5.278 PAC:16421393 Carica papaya 399  
evm.model.supercontig_74.73 PAC:16425767 Carica papaya 724  
evm.model.supercontig_9.52 PAC:16428318 Carica papaya 777  
evm.model.supercontig_9.55 PAC:16428321 Carica papaya 664  
evm.model.supercontig_95.43 PAC:16428884 Carica papaya 541  
29693.m002076 B9S180 PAC:16806046 Ricinus communis 1131  
29736.m002040 B9S2C2 PAC:16807145 Ricinus communis 375  
29848.m004482 B9RNQ2 PAC:16811139 Ricinus communis 930  
29889.m003301 B9RZR1 PAC:16812248 Ricinus communis 1141  
29889.m003302 B9RZR2 PAC:16812249 Ricinus communis 796  
30128.m008997 B9RFS7 PAC:16818581 Ricinus communis 1124  
30130.m000276 B9T0R3 PAC:16818669 Ricinus communis 1006  
30162.m001273 B9RKW8 PAC:16820952 Ricinus communis 984  
30190.m011340 B9RC41 PAC:16823694 Ricinus communis 730  
30651.m000015 B9TEQ3 PAC:16824526 Ricinus communis 485  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9301332
            15009198
            12377121
            10357859