Protein Domain : IPR013767

Type:  Domain Name:  PAS fold
Description:  PAS domains are involved in many signalling proteins where they are used as a signal sensor domain []. PAS domains appear in archaea,bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Haeme,flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. The PAS domain was named after three proteins that itoccurs in: Per- period circadian proteinArnt- Ah receptor nuclear translocator proteinSim- single-minded protein.PAS domains are often associated with PAC domains . It appears that these domains are directly linked, and that together they form the conserved 3D PAS fold. The division between the PAS and PAC domains is caused by major differences in sequences in the region connecting these two motifs []. In human PAS kinase, this region has been shown to be very flexible, and adopts different conformations depending on the bound ligand [].Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels []. Short Name:  PAS_fold
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0 Child Features

2 Contains

DB identifier Type Name
IPR000700 Domain PAS-associated, C-terminal
IPR001610 Repeat PAC motif

1 Cross References

Identifier
PF00989

11 Found Ins

DB identifier Type Name
IPR012129 Family Phytochrome A/B/C/D/E
IPR001294 Family Phytochrome
IPR014310 Family Signal transduction histidine kinase, phosphate regulon sensor PhoR
IPR003949 Family Potassium channel, voltage-dependent, EAG
IPR014409 Family Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB
IPR014285 Family Nitrogen fixation negative regulator NifL
IPR016384 Family Plasmid transfer regulator TraJ, R1 plasmid
IPR011785 Family Transcription regulator PpsR
IPR017426 Family Nuclear receptor coactivator
IPR012130 Family Photoactive yellow-protein
IPR001067 Family Nuclear translocator

1 GO Annotation

GO Term Gene Name
GO:0006355 IPR013767

1 Ontology Annotations

GO Term Gene Name
GO:0006355 IPR013767

1 Parent Features

DB identifier Type Name
IPR000014 Domain PAS domain

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
161430 D8T691 PAC:15401681 Selaginella moellendorffii 1143  
evm.model.supercontig_17.112 PAC:16410603 Carica papaya 1112  
evm.model.supercontig_48.231 PAC:16420875 Carica papaya 986  
evm.model.supercontig_74.73 PAC:16425767 Carica papaya 724  
29693.m002076 B9S180 PAC:16806046 Ricinus communis 1131  
29889.m003301 B9RZR1 PAC:16812248 Ricinus communis 1141  
30128.m008997 B9RFS7 PAC:16818581 Ricinus communis 1124  
30190.m011340 B9RC41 PAC:16823694 Ricinus communis 730  
47994.m000013 B9TP00 PAC:16828047 Ricinus communis 270  
28953.m000080 B9T8Z0 PAC:16802020 Ricinus communis 342  
Cucsa.005340.1 PAC:16951131 Cucumis sativus 1148  
Cucsa.005370.1 A0A0A0KJ32 PAC:16951135 Cucumis sativus 1123  
Cucsa.005370.2 PAC:16951136 Cucumis sativus 978  
Cucsa.100300.1 A0A0A0K6F8 PAC:16958550 Cucumis sativus 1119  
Cucsa.212560.1 PAC:16969357 Cucumis sativus 1123  
Cucsa.252520.1 A0A0A0L825 PAC:16971956 Cucumis sativus 1132  
orange1.1g002210m A0A067DDU1 PAC:18132623 Citrus sinensis 953  
orange1.1g005722m A0A067DPT2 PAC:18132624 Citrus sinensis 681  
orange1.1g001215m A0A067DR09 PAC:18132622 Citrus sinensis 1122  
orange1.1g002191m A0A067GRT1 PAC:18112278 Citrus sinensis 955  
orange1.1g001210m A0A067GEJ2 PAC:18112275 Citrus sinensis 1123  
orange1.1g001353m A0A067GE87 PAC:18112276 Citrus sinensis 1093  
orange1.1g002152m A0A067GH87 PAC:18112277 Citrus sinensis 959  
orange1.1g037299m A0A067G8U7 PAC:18109781 Citrus sinensis 1111  
orange1.1g003963m PAC:18109642 Citrus sinensis 783  
orange1.1g005054m A0A067G0L9 PAC:18109644 Citrus sinensis 716  
orange1.1g005841m A0A067G958 PAC:18109645 Citrus sinensis 674  
orange1.1g003978m PAC:18109643 Citrus sinensis 782  
orange1.1g038211m A0A067FBJ7 PAC:18120324 Citrus sinensis 605  
orange1.1g001564m A0A067EMQ0 PAC:18129991 Citrus sinensis 1052  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9301332
            15009198
            12377121
            10357859