Protein Domain : IPR014285

Type:  Family Name:  Nitrogen fixation negative regulator NifL
Description:  NifL from Azotobacter vinelandiisenses both the redox and fixed nitrogen status to regulate nitrogen fixation. NifL acts by modulating the activity of the nitrogen fixation positive regulator protein NifA: NifL inhibits NifA in response to oxygen and low level of fixed nitrogen. NifA and NifL are encoded by adjacent genes. NifL is FAD-containing, and has a domain architecture similar to that of the cytoplasmic histidine protein kinases, containing two N-terminal PAS domains and a C-terminal transmitter region containing a conserved histidine residue (H domain) and a nucleotide binding GHKL domain corresponding to the catalytic core of the histidine kinases []. However, NifL does not exhibit kinase activity and regulates its partner NifA by direct protein-protein interactions rather than phosphorylation. Short Name:  N_fixation_neg-reg_NifL
Paste the following link

0 Child Features

6 Contains

DB identifier Type Name
IPR003594 Domain Histidine kinase-like ATPase, C-terminal domain
IPR004358 Domain Signal transduction histidine kinase-related protein, C-terminal
IPR000014 Domain PAS domain
IPR000700 Domain PAS-associated, C-terminal
IPR013767 Domain PAS fold
IPR001610 Repeat PAC motif

1 Cross References

Identifier
TIGR02938

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004871 IPR014285
GO:0050660 IPR014285
GO:0007165 IPR014285
GO:0009399 IPR014285

4 Ontology Annotations

GO Term Gene Name
GO:0004871 IPR014285
GO:0050660 IPR014285
GO:0007165 IPR014285
GO:0009399 IPR014285

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17355964