Protein Domain : IPR003043

Type:  Conserved_site Name:  Uroporphiryn-III C-methyltransferase, conserved site
Description:  S-adenosyl-L-methionine-dependent uroporphyrinogen III C-methyltransferase (SUMT; ) is likely to be involved in the biosynthesis of siroheme and cobalamin []. Siroheme, the prosthetic group for both nitrite and sulphite reductases, is a methylated, iron-containing modified tetrapyrrole. This enzyme is found in a wide taxonomic range: archaebacteria, eukaryotes and bacteria.S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase from Arabidopsis thalianamay catalyze transmethylation in a multistep process involving the formation of a covalently linked complex with S-adenosyl-L-methionine. The product has a sequence at the amino terminus that resembles a transit peptide for localization to mitochondria or plastids []. Short Name:  Uropor_MeTrfase_CS
Paste the following link

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PS00839
PS00840

7 Found Ins

DB identifier Type Name
IPR014777 Domain Tetrapyrrole methylase, subdomain 1
IPR000878 Domain Tetrapyrrole methylase
IPR006366 Domain Uroporphyrin-III C-methyltransferase
IPR006362 Domain Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase
IPR012383 Family Uroporphyrin-III C-methyltransferase, plant
IPR012066 Family Uroporphyrin-III C-methyltransferase, yeast
IPR012409 Family Sirohaem synthase

4 GO Annotations

GO Term Gene Name
GO:0008168 IPR003043
GO:0043115 IPR003043
GO:0006779 IPR003043
GO:0055114 IPR003043

4 Ontology Annotations

GO Term Gene Name
GO:0008168 IPR003043
GO:0043115 IPR003043
GO:0006779 IPR003043
GO:0055114 IPR003043

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1856165
            9006913