Protein Domain : IPR004218

Type:  Domain Name:  Prokaryotic glutathione synthetase, ATP-binding
Description:  Prokaryotic glutathione synthetase (glutathione synthase) catalyses the conversion of gamma-L-glutamyl-L-cysteine and glycine to orthophosphate and glutathione in the presence of ATP. This is the second step in glutathione biosynthesis. The enzyme is inhibited by 7,8-dihydrofolate, methotrexate and trimethoprim. This is the ATP-binding domain of the enzyme. Short Name:  GSHS_ATP-bd
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0 Child Features

1 Contains

DB identifier Type Name
IPR013816 Domain ATP-grasp fold, subdomain 2

1 Cross References

Identifier
PF02955

1 Found In

DB identifier Type Name
IPR006284 Family Glutathione synthetase, prokaryotic

3 GO Annotations

GO Term Gene Name
GO:0004363 IPR004218
GO:0005524 IPR004218
GO:0006750 IPR004218

3 Ontology Annotations

GO Term Gene Name
GO:0004363 IPR004218
GO:0005524 IPR004218
GO:0006750 IPR004218

1 Parent Features

DB identifier Type Name
IPR011761 Domain ATP-grasp fold

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1008982m.p PAC:33622929 Brachypodium distachyon Pangenome 262  
Brdisv1pangenome1010825m.p PAC:33620883 Brachypodium distachyon Pangenome 258  
Brdisv1BdTR11A1049464m.p PAC:35690209 Brachypodium distachyon BdTR11a 281  
Brdisv1BdTR11A1045383m.p PAC:35690441 Brachypodium distachyon BdTR11a 313  
Brdisv1BdTR11A1041516m.p PAC:35694154 Brachypodium distachyon BdTR11a 231  

0 Publications