GO Term : GO:0004363 glutathione synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0004363 121129 GO
GOAnnotation GO:0004363 121129  
GOAnnotation GO:0004363 123989  
OntologyAnnotation GO:0004363 123989 GO
OntologyAnnotation GO:0004363 425362 GO
GOAnnotation GO:0004363 425362  
GOAnnotation GO:0004363 418835  
OntologyAnnotation GO:0004363 418834 GO
GOAnnotation GO:0004363 418834  
OntologyAnnotation GO:0004363 418835 GO
GOAnnotation GO:0004363 evm.TU.supercontig_48.5  
OntologyAnnotation GO:0004363 evm.model.supercontig_48.5 GO
GOAnnotation GO:0004363 29719.t000021  
OntologyAnnotation GO:0004363 29719.m000334 GO
GOAnnotation GO:0004363 29737.t000041  
OntologyAnnotation GO:0004363 29737.m001247 GO
GOAnnotation GO:0004363 30128.t000186  
OntologyAnnotation GO:0004363 30128.m008725 GO
OntologyAnnotation GO:0004363 Cucsa.163590.1 GO
OntologyAnnotation GO:0004363 Cucsa.163590.2 GO
GOAnnotation GO:0004363 Cucsa.163590  
OntologyAnnotation GO:0004363 orange1.1g008481m GO
OntologyAnnotation GO:0004363 orange1.1g008446m GO
OntologyAnnotation GO:0004363 orange1.1g008309m GO
GOAnnotation GO:0004363 orange1.1g008309m.g  
OntologyAnnotation GO:0004363 AT2G35345.1 GO
GOAnnotation GO:0004363 AT2G35345  
OntologyAnnotation GO:0004363 AT5G27380.1 GO
GOAnnotation GO:0004363 AT5G27380  
OntologyAnnotation GO:0004363 Thhalv10022204m GO

30 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006749 glutathione metabolic process The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006790 sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0016881 acid-amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0006750 glutathione biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
GO:0042398 cellular modified amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0043043 peptide biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.
GO:0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0004363 glutathione synthase activity Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0006518 peptide metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:0043604 amide biosynthetic process The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
GO:1901566 organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organonitrogen compound.
GO:0043603 cellular amide metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
GO:0044271 cellular nitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
GO:1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving organonitrogen compound.
GO:0006575 cellular modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0044272 sulfur compound biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0019184 nonribosomal peptide biosynthetic process The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.

29 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0006750 GO:0004363
is_a GO:0016881 GO:0004363
part of GO:0006749 GO:0004363
is_a GO:0016874 GO:0004363
part of GO:0006807 GO:0004363
is_a GO:0016879 GO:0004363
part of GO:1901566 GO:0004363
part of GO:1901564 GO:0004363
part of GO:0071704 GO:0004363
part of GO:0008150 GO:0004363
part of GO:0008152 GO:0004363
part of GO:0043604 GO:0004363
part of GO:0043603 GO:0004363
is_a GO:0003674 GO:0004363
part of GO:0006790 GO:0004363
part of GO:0034641 GO:0004363
part of GO:0044237 GO:0004363
part of GO:0006575 GO:0004363
part of GO:0009987 GO:0004363
part of GO:0019184 GO:0004363
part of GO:0044271 GO:0004363
part of GO:0006518 GO:0004363
part of GO:0042398 GO:0004363
part of GO:1901576 GO:0004363
part of GO:0043043 GO:0004363
part of GO:0044272 GO:0004363
part of GO:0009058 GO:0004363
part of GO:0044249 GO:0004363
is_a GO:0003824 GO:0004363

3 Synonyms

Name Type
gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming) synonym
GSH synthetase activity synonym
glutathione synthetase activity synonym