Protein Domain : IPR014183

Type:  Family Name:  Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase
Description:  The members of this protein family show dual function. First, they remove formaldehyde, a toxic metabolite, by acting as S-(hydroxymethyl)glutathione dehydrogenase (). S-(hydroxymethyl)glutathione can form spontaneously from formaldehyde and glutathione, and so this enzyme previously was designated glutathione-dependent formaldehyde dehydrogenase. These same proteins are also designated as class III alcohol dehydrogenases (), i.e. alcohol dehydrogenases that do not require glutathione and they tend to show poor activity for ethanol among their various substrate alcohols. Short Name:  ADH_3
Paste the following link

0 Child Features

3 Contains

DB identifier Type Name
IPR013154 Domain Alcohol dehydrogenase, N-terminal
IPR013149 Domain Alcohol dehydrogenase, C-terminal
IPR002328 Conserved_site Alcohol dehydrogenase, zinc-type, conserved site

1 Cross References

Identifier
TIGR02818

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0008270 IPR014183
GO:0051903 IPR014183
GO:0006069 IPR014183
GO:0055114 IPR014183

4 Ontology Annotations

GO Term Gene Name
GO:0008270 IPR014183
GO:0051903 IPR014183
GO:0006069 IPR014183
GO:0055114 IPR014183

1 Parent Features

DB identifier Type Name
IPR002085 Family Alcohol dehydrogenase superfamily, zinc-type

401 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
149322 D8RRY0 PAC:15409927 Selaginella moellendorffii 380  
evm.model.supercontig_87.56 PAC:16427725 Carica papaya 379  
29885.m000144 B9T5W1 PAC:16812148 Ricinus communis 379  
Cucsa.348790.1 A0A0A0KBZ1 PAC:16979660 Cucumis sativus 379  
orange1.1g017431m A0A067FEE9 PAC:18131825 Citrus sinensis 371  
orange1.1g019139m A0A067FEE3 PAC:18131826 Citrus sinensis 345  
orange1.1g017000m A0A067FQN4 PAC:18131824 Citrus sinensis 379  
orange1.1g016978m A0A067FQN4 PAC:18131823 Citrus sinensis 379  
AT5G43940.1 Q96533 PAC:19669622 Arabidopsis thaliana 379  
AT5G43940.2 F4K7D6 PAC:19669621 Arabidopsis thaliana 391  
Thhalv10003232m V4LLL2 PAC:20207986 Eutrema salsugineum 372  
Thhalv10003230m V4L2T4 PAC:20207985 Eutrema salsugineum 379  
Ciclev10020679m V4VUK6 PAC:20811151 Citrus clementina 371  
Ciclev10020620m V4TYV5 PAC:20811150 Citrus clementina 379  
Potri.002G254900.6 A0A2K2BPI4 PAC:27022927 Populus trichocarpa 379  
Potri.002G254900.1 PAC:27022926 Populus trichocarpa 389  
Gorai.001G236500.1 A0A0D2Q3L5 PAC:26820692 Gossypium raimondii 379  
53256 I0Z0L6 PAC:27390983 Coccomyxa subellipsoidea C-169 384  
56654 C1E0V8 PAC:27398570 Micromonas sp RCC299 681  
Thecc1EG003851t1 A0A061DQB3 PAC:27433451 Theobroma cacao 379  
Thecc1EG003851t2 A0A061DPD6 PAC:27433452 Theobroma cacao 341  
Migut.N02236.1.p A0A022PR62 PAC:28926098 Mimulus guttatus 378  
Araha.49363s0001.1.p PAC:28842305 Arabidopsis halleri 347  
Cagra.5198s0003.1.p PAC:28899636 Capsella grandiflora 379  
Glyma.10G041000.1.p I1L8I0 PAC:30476505 Glycine max 380  
Glyma.03G168700.3.p I1JP98 PAC:30516130 Glycine max 362  
Glyma.03G168700.2.p I1JP97 PAC:30516129 Glycine max 372  
Glyma.03G168700.1.p I1JP95 PAC:30516128 Glycine max 379  
Glyma.19G170100.1.p I1N9X0 PAC:30512288 Glycine max 379  
Brara.F03778.1.p A0A397ZBV9 PAC:30627881 Brassica rapa FPsc 379  

0 Publications