Protein Domain : IPR000965

Type:  Domain Name:  GPR domain
Description:  Gamma-glutamyl phosphate reductase () (GPR) is the enzyme that catalyses the second step in the biosynthesis of proline from glutamate, the NADP-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. In bacteria (gene proA) and yeast [] (gene PRO2), GPR is a monofunctional protein, while in plants and mammals, it is a bifunctional enzyme (P5CS) [] that consists of two domains, an N-terminal glutamate 5-kinase domain () and a C-terminal GPR domain. This entry represents the C-terminal GPR domain of the gamma-glutamyl phosphate reductase. Short Name:  GPR_dom
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0 Child Features

3 Contains

DB identifier Type Name
IPR016163 Domain Aldehyde dehydrogenase, C-terminal
IPR016162 Domain Aldehyde dehydrogenase N-terminal domain
IPR020593 Conserved_site Gamma-glutamyl phosphate reductase GPR, conserved site

2 Cross Referencess

Identifier
TIGR00407
MF_00412

1 Found In

DB identifier Type Name
IPR005766 Family Delta l-pyrroline-5-carboxylate synthetase

3 GO Annotations

GO Term Gene Name
GO:0004350 IPR000965
GO:0006561 IPR000965
GO:0055114 IPR000965

3 Ontology Annotations

GO Term Gene Name
GO:0004350 IPR000965
GO:0006561 IPR000965
GO:0055114 IPR000965

1 Parent Features

DB identifier Type Name
IPR015590 Domain Aldehyde dehydrogenase domain

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
410685 D8RFI6 PAC:15407190 Selaginella moellendorffii 771  
evm.model.supercontig_454.3 PAC:16420362 Carica papaya 721  
30143.m001194 B9SE11 PAC:16819514 Ricinus communis 732  
Cucsa.136260.1 PAC:16963076 Cucumis sativus 725  
Cucsa.136260.10 A0A0A0KBH3 PAC:16963077 Cucumis sativus 717  
Cucsa.175750.2 PAC:16966798 Cucumis sativus 614  
Cucsa.175750.1 PAC:16966797 Cucumis sativus 614  
orange1.1g005131m A0A067FP92 PAC:18138383 Citrus sinensis 713  
orange1.1g005062m A0A067DZ72 PAC:18103445 Citrus sinensis 715  
orange1.1g008588m A0A067DZ78 PAC:18103448 Citrus sinensis 560  
orange1.1g005798m A0A067EA90 PAC:18103446 Citrus sinensis 676  
orange1.1g004665m A0A067E2Q7 PAC:18103439 Citrus sinensis 738  
orange1.1g005041m A0A067DYR2 PAC:18103440 Citrus sinensis 717  
orange1.1g005047m A0A067EB43 PAC:18103441 Citrus sinensis 716  
orange1.1g005074m A0A067DZ72 PAC:18103443 Citrus sinensis 715  
orange1.1g005078m A0A067DZ72 PAC:18103442 Citrus sinensis 715  
orange1.1g005079m A0A067DZ72 PAC:18103444 Citrus sinensis 715  
orange1.1g006484m A0A067EB49 PAC:18103447 Citrus sinensis 643  
AT3G55610.1 P54888 PAC:19660432 Arabidopsis thaliana 726  
AT3G55610.2 B3H5E3 PAC:19660433 Arabidopsis thaliana 622  
AT2G39800.2 B9DFG0 PAC:19638513 Arabidopsis thaliana 614  
AT2G39800.3 F4IFZ9 PAC:19638512 Arabidopsis thaliana 714  
AT2G39800.4 P54887 PAC:19638511 Arabidopsis thaliana 717  
AT2G39800.1 P54887 PAC:19638510 Arabidopsis thaliana 717  
Thhalv10016320m V4LQ23 PAC:20180100 Eutrema salsugineum 716  
Thhalv10016321m V4LQ23 PAC:20180099 Eutrema salsugineum 716  
Thhalv10016326m V4MJA1 PAC:20180101 Eutrema salsugineum 708  
Thhalv10016322m V4LQ23 PAC:20180098 Eutrema salsugineum 716  
Thhalv10010200m V4LMA6 PAC:20207425 Eutrema salsugineum 630  
Thhalv10010150m V4L3K1 PAC:20207424 Eutrema salsugineum 733  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1384052
            8896266