Protein Domain : IPR008979

Type:  Domain Name:  Galactose-binding domain-like
Description:  Proteins containing a galactose-binding domain-like fold can be found in several different protein families, in both eukaryotes and prokaryotes. The common function of these domains is to bind to specific ligands, such as cell-surface-attached carbohydrate substrates for galactose oxidase and sialidase [], phospholipids on the outer side of the mammalian cell membrane for coagulation factor Va [], membrane-anchored ephrin for the Eph family of receptor tyrosine kinases [], and a complex of broken single-stranded DNA and DNA polymerase beta for XRCC1 [].The structure of the galactose-binding domain-like members consists of a beta-sandwich, in which the strands making up the sheets exhibit a jellyroll fold. There is a high degree of similarity in the beta-sandwich and in the loops between different family members, despite an often low level of sequence similarity. Short Name:  Galactose-bd-like
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20 Child Features

DB identifier Type Name
IPR003305 Domain Carbohydrate-binding, CenC-like
IPR006104 Domain Glycosyl hydrolases family 2, sugar binding domain
IPR015176 Domain Lyase, N-terminal
IPR005087 Domain Carbohydrate binding module family 11
IPR000421 Domain Coagulation factor 5/8 C-terminal domain
IPR029411 Domain Rhamnogalacturonan lyase, domain III
IPR010400 Domain PITH domain
IPR010565 Domain Muskelin, N-terminal
IPR025300 Domain Beta-galactosidase jelly roll domain
IPR002706 Domain DNA-repair protein Xrcc1, N-terminal
IPR013736 Domain Xaa-Pro dipeptidyl-peptidase, C-terminal
IPR013222 Domain Glycosyl hydrolase family 98, putative carbohydrate-binding module
IPR005084 Domain Carbohydrate binding module family 6
IPR015908 Domain Allantoicase domain
IPR006588 Domain Peptide N glycanase, PAW domain
IPR001090 Domain Ephrin receptor ligand binding domain
IPR005088 Domain Carbohydrate binding module family 15
IPR005086 Domain Carbohydrate binding module family 17/28
IPR005638 Domain Delta endotoxin, C-terminal
IPR015295 Domain Carbohydrate binding module 27

1 Contains

DB identifier Type Name
IPR001426 Conserved_site Tyrosine-protein kinase, receptor class V, conserved site

2 Cross Referencess

Identifier
G3DSA:2.60.120.260
SSF49785

12 Found Ins

DB identifier Type Name
IPR001944 Family Glycoside hydrolase, family 35
IPR016901 Family Anaphase-promoting complex, subunit 10
IPR006585 Domain Fucolectin tachylectin-4 pentraxin-1
IPR012905 Family PA-IL-like
IPR016257 Family Ephrin receptor type-A /type-B
IPR016590 Family Rhamnogalacturonase B
IPR016625 Family Uncharacterised conserved protein UCP014872, subtilisin-related
IPR008252 Family Peptidase S15, X-Pro dipeptidyl-peptidase
IPR017319 Family Subtilisin-like serine protease TK1689-type
IPR017323 Family Lysyl endopeptidase
IPR020766 Family Receptor-like tyrosine-protein kinase kin-15/kin-16
IPR010900 Family Nicotine adenine dinucleotide glycohydrolase

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
410607 D8RF99 PAC:15407013 Selaginella moellendorffii 325  
92145 D8RFI1 PAC:15416149 Selaginella moellendorffii 692  
411384 D8RHG7 PAC:15407842 Selaginella moellendorffii 469  
411383 D8RHG6 PAC:15407841 Selaginella moellendorffii 585  
441228 D8RHG5 PAC:15406267 Selaginella moellendorffii 492  
431234 D8TBZ0 PAC:15421345 Selaginella moellendorffii 261  
431526 D8TCY4 PAC:15401363 Selaginella moellendorffii 205  
236749 D8TCX7 PAC:15411400 Selaginella moellendorffii 466  
431528 D8TCY6 PAC:15401366 Selaginella moellendorffii 214  
412226 D8RKH4 PAC:15409971 Selaginella moellendorffii 255  
412246 D8RKJ1 PAC:15410027 Selaginella moellendorffii 326  
441539 D8RKH9 PAC:15408562 Selaginella moellendorffii 537  
431829 D8TDY1 PAC:15403612 Selaginella moellendorffii 393  
431838 D8TDY8 PAC:15403636 Selaginella moellendorffii 387  
431833 D8TDY4 PAC:15403628 Selaginella moellendorffii 325  
138182 D8TER8 PAC:15420716 Selaginella moellendorffii 317  
96868 D8RLU1 PAC:15410956 Selaginella moellendorffii 174  
438140 D8QUD1 PAC:15418881 Selaginella moellendorffii 792  
413650 D8RPS3 PAC:15416065 Selaginella moellendorffii 805  
413798 D8RQ90 PAC:15416897 Selaginella moellendorffii 667  
413794 D8RQ86 PAC:15416890 Selaginella moellendorffii 561  
442725 D8RVK3 PAC:15413117 Selaginella moellendorffii 1213  
103154 D8RW11 PAC:15406732 Selaginella moellendorffii 481  
415432 D8RW40 PAC:15420280 Selaginella moellendorffii 336  
415429 D8RW37 PAC:15420268 Selaginella moellendorffii 237  
415483 D8RW94 PAC:15420406 Selaginella moellendorffii 324  
415436 D8RW43 PAC:15420284 Selaginella moellendorffii 134  
442783 D8RW33 PAC:15413259 Selaginella moellendorffii 380  
404798 D8QXE4 PAC:15412629 Selaginella moellendorffii 874  
267967 D8RYZ7 PAC:15415154 Selaginella moellendorffii 648  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11780069
            10467102
            2002850
            10586886