28 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0003677 | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| GO:0005488 | binding | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
| GO:0003676 | nucleic acid binding | Interacting selectively and non-covalently with any nucleic acid. |
| GO:0051276 | chromosome organization | A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. |
| GO:0008219 | cell death | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo. |
| GO:0006915 | apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| GO:0030261 | chromosome condensation | The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. |
| GO:0016043 | cellular component organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:0009987 | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0006323 | DNA packaging | Any process in which DNA and associated proteins are formed into a compact, orderly structure. |
| GO:0006996 | organelle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0044763 | single-organism cellular process | Any process that is carried out at the cellular level, occurring within a single organism. |
| GO:0044699 | single-organism process | A biological process that involves only one organism. |
| GO:0071840 | cellular component organization or biogenesis | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:1902589 | single-organism organelle organization | An organelle organization which involves only one organism. |
| GO:0008150 | biological_process | Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
| GO:0003674 | molecular_function | Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
| GO:1901363 | heterocyclic compound binding | Interacting selectively and non-covalently with heterocyclic compound. |
| GO:0097159 | organic cyclic compound binding | Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. |
| GO:0022411 | cellular component disassembly | A cellular process that results in the breakdown of a cellular component. |
| GO:0071103 | DNA conformation change | A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. |
| GO:0016265 | death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. |
| GO:0012501 | programmed cell death | A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. |
| GO:0030262 | apoptotic nuclear changes | Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. |
| GO:0097194 | execution phase of apoptosis | A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. |
| GO:0008301 | DNA binding, bending | The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. |
| GO:0030263 | apoptotic chromosome condensation | The compaction of chromatin during apoptosis. |
33 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0030262 | GO:0030263 |
| is_a | GO:0030261 | GO:0030263 |
| part of | GO:0006915 | GO:0030263 |
| has_part | GO:0008301 | GO:0030263 |
| has_part | GO:1901363 | GO:0030263 |
| part of | GO:0044699 | GO:0030263 |
| is_a | GO:0006323 | GO:0030263 |
| is_a | GO:0044699 | GO:0030263 |
| part of | GO:0009987 | GO:0030263 |
| part of | GO:0008219 | GO:0030263 |
| part of | GO:0016265 | GO:0030263 |
| part of | GO:0016043 | GO:0030263 |
| has_part | GO:0097159 | GO:0030263 |
| has_part | GO:0003677 | GO:0030263 |
| has_part | GO:0003676 | GO:0030263 |
| part of | GO:0097194 | GO:0030263 |
| is_a | GO:0016043 | GO:0030263 |
| is_a | GO:0051276 | GO:0030263 |
| has_part | GO:0003674 | GO:0030263 |
| is_a | GO:0071103 | GO:0030263 |
| is_a | GO:0071840 | GO:0030263 |
| part of | GO:0071840 | GO:0030263 |
| part of | GO:0044763 | GO:0030263 |
| part of | GO:0022411 | GO:0030263 |
| is_a | GO:0008150 | GO:0030263 |
| is_a | GO:0006996 | GO:0030263 |
| part of | GO:0006921 | GO:0030263 |
| is_a | GO:0009987 | GO:0030263 |
| is_a | GO:1902589 | GO:0030263 |
| is_a | GO:0044763 | GO:0030263 |
