13 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0008219 | cell death | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo. |
| GO:0006915 | apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| GO:0016043 | cellular component organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:0009987 | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0044763 | single-organism cellular process | Any process that is carried out at the cellular level, occurring within a single organism. |
| GO:0044699 | single-organism process | A biological process that involves only one organism. |
| GO:0071840 | cellular component organization or biogenesis | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:0008150 | biological_process | Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
| GO:0022411 | cellular component disassembly | A cellular process that results in the breakdown of a cellular component. |
| GO:0016265 | death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. |
| GO:0012501 | programmed cell death | A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. |
| GO:0097194 | execution phase of apoptosis | A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. |
27 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0006921 | GO:0006309 |
| is_a | GO:0022411 | GO:0006921 |
| part of | GO:0097194 | GO:0006921 |
| is_a | GO:0022411 | GO:0006921 |
| part of | GO:0097194 | GO:0006921 |
| is_a | GO:0044699 | GO:0006921 |
| part of | GO:0008219 | GO:0006921 |
| part of | GO:0009987 | GO:0006921 |
| is_a | GO:0016043 | GO:0006921 |
| is_a | GO:0071840 | GO:0006921 |
| is_a | GO:0044763 | GO:0006921 |
| part of | GO:0006915 | GO:0006921 |
| part of | GO:0012501 | GO:0006921 |
| part of | GO:0016265 | GO:0006921 |
| is_a | GO:0009987 | GO:0006921 |
| part of | GO:0008150 | GO:0006921 |
| is_a | GO:0008150 | GO:0006921 |
| part of | GO:0044763 | GO:0006921 |
| part of | GO:0044699 | GO:0006921 |
| is_a | GO:0006921 | GO:0030262 |
| part of | GO:0006921 | GO:0030263 |
| part of | GO:0006921 | GO:0030264 |
| regulates | GO:0006921 | GO:1902510 |
| regulates | GO:0006921 | GO:1902511 |
| negatively regulates | GO:0006921 | GO:1902511 |
| regulates | GO:0006921 | GO:1902512 |
| positively regulates | GO:0006921 | GO:1902512 |
