Protein Domain : IPR011236

Type:  Family Name:  Serine/threonine protein phosphatase 5
Description:  These eukaryotic serine/threonine phosphoprotein phosphatases, first described from human (PP5) and Saccharomyces cerevisiae(PPT1), are distinguished from related protein phosphatases by an N-terminal region of about 200 residues that contains three tandem tetratricopeptide repeats (TPR) []. Structurally, TPR repeats form a helical scaffold of antiparallel alpha-helices with anamphipathic groove that mediates protein-protein interactions []. The TPR domainscontribute to regulation of PP5 activity, which is normally low but stimulated by interaction with lipid [], and to interaction with other proteins []. Short Name:  Ser/Thr_PPase_5
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0 Child Features

5 Contains

DB identifier Type Name
IPR013235 Domain PPP domain
IPR011990 Domain Tetratricopeptide-like helical domain
IPR013026 Domain Tetratricopeptide repeat-containing domain
IPR006186 Domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR001440 Repeat Tetratricopeptide repeat 1

1 Cross References

Identifier
PTHR11668:SF12

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004721 IPR011236
GO:0006470 IPR011236
GO:0005634 IPR011236
GO:0005737 IPR011236

4 Ontology Annotations

GO Term Gene Name
GO:0004721 IPR011236
GO:0006470 IPR011236
GO:0005634 IPR011236
GO:0005737 IPR011236

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9482716
            11523989
            11504734
            7925273