GO Term : GO:0004721 phosphoprotein phosphatase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004721 179725  
OntologyAnnotation GO:0004721 179725 GO
OntologyAnnotation GO:0004721 167775 GO
GOAnnotation GO:0004721 167775  
GOAnnotation GO:0004721 89210  
OntologyAnnotation GO:0004721 89210 GO
OntologyAnnotation GO:0004721 23521 GO
GOAnnotation GO:0004721 23521  
GOAnnotation GO:0004721 91859  
OntologyAnnotation GO:0004721 91859 GO
GOAnnotation GO:0004721 411029  
OntologyAnnotation GO:0004721 411029 GO
GOAnnotation GO:0004721 79490  
OntologyAnnotation GO:0004721 79490 GO
OntologyAnnotation GO:0004721 175932 GO
GOAnnotation GO:0004721 175932  
GOAnnotation GO:0004721 405568  
OntologyAnnotation GO:0004721 405568 GO
OntologyAnnotation GO:0004721 evm.TU.contig_35379.1 GO
GOAnnotation GO:0004721 evm.TU.contig_35379  
GOAnnotation GO:0004721 evm.TU.supercontig_147.28  
OntologyAnnotation GO:0004721 evm.model.supercontig_147.28 GO
GOAnnotation GO:0004721 evm.TU.supercontig_18.73  
OntologyAnnotation GO:0004721 evm.model.supercontig_18.73 GO
OntologyAnnotation GO:0004721 evm.model.supercontig_38.29 GO
GOAnnotation GO:0004721 evm.TU.supercontig_38.29  
OntologyAnnotation GO:0004721 evm.model.supercontig_64.48 GO
GOAnnotation GO:0004721 evm.TU.supercontig_64.48  
OntologyAnnotation GO:0004721 evm.model.supercontig_9.147 GO
GOAnnotation GO:0004721 evm.TU.supercontig_9.147  

24 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006470 protein dephosphorylation The process of removing one or more phosphoric residues from a protein.
GO:0016311 dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
GO:0016791 phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0042578 phosphoric ester hydrolase activity Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0004721 phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0036211 protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

100 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0006470 GO:0004721
is_a GO:0016791 GO:0004721
part of GO:0009987 GO:0004721
is_a GO:0042578 GO:0004721
is_a GO:0016787 GO:0004721
part of GO:0036211 GO:0004721
part of GO:0044260 GO:0004721
part of GO:0043170 GO:0004721
part of GO:0019538 GO:0004721
is_a GO:0003824 GO:0004721
part of GO:0043412 GO:0004721
part of GO:0044237 GO:0004721
part of GO:0016311 GO:0004721
part of GO:0071704 GO:0004721
part of GO:0044267 GO:0004721
part of GO:0008150 GO:0004721
is_a GO:0003674 GO:0004721
part of GO:0008152 GO:0004721
is_a GO:0016788 GO:0004721
part of GO:0006793 GO:0004721
part of GO:0006464 GO:0004721
part of GO:0006796 GO:0004721
part of GO:0044238 GO:0004721
is_a GO:0004721 GO:0004722
is_a GO:0004721 GO:0004723
is_a GO:0004721 GO:0004724
is_a GO:0004721 GO:0004725
is_a GO:0004721 GO:0004726
is_a GO:0004721 GO:0004727
is_a GO:0004721 GO:0004728

6 Synonyms

Name Type
phosphoprotein phosphohydrolase activity synonym
protein phosphatase-1 activity synonym
protein phosphatase activity synonym
protein phosphatase-2B activity synonym
protein phosphatase-2A activity synonym
protein phosphatase-2C activity synonym