Protein Domain : IPR016242

Type:  Family Name:  Serine/threonine-protein kinase Mps1
Description:  Mps1 is a serine/threonine-protein kinase involved in the phosphorylation of many mitotic regulators. It is required for spindle pole body (SPB) duplication and spindle checkpoint function [, ]. It is involved in sister chromatid biorientation in mitosis and meiosis []. The expression of Mps1 is regulated in a cell cycle-dependent manner, and the activity of Mps1 can be regulated through autophosphorylation []. Short Name:  Mps1
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0 Child Features

5 Contains

DB identifier Type Name
IPR000719 Domain Protein kinase domain
IPR011009 Domain Protein kinase-like domain
IPR002290 Domain Serine/threonine/dual specificity protein kinase, catalytic domain
IPR017441 Binding_site Protein kinase, ATP binding site
IPR008271 Active_site Serine/threonine-protein kinase, active site

1 Cross References

Identifier
PIRSF000611

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0004674 IPR016242
GO:0004712 IPR016242
GO:0006468 IPR016242
GO:0007094 IPR016242
GO:0030474 IPR016242

5 Ontology Annotations

GO Term Gene Name
GO:0004674 IPR016242
GO:0004712 IPR016242
GO:0006468 IPR016242
GO:0007094 IPR016242
GO:0030474 IPR016242

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17728254
            7737118
            8567717
            23371552