Protein Domain : IPR016362

Type:  Family Name:  POU-domain transcription factor, class 3
Description:  This group represents a group of POU-domain transcription factors, brain type (class III). They are thought to be involved brain development [, ].The POU factors interact with canonical octamer sequence ATGCAAAT through its POU-specific (POU-S) domain and POU homeodomain (POU-H). The POU homeodomain of the class III factors interacts with a noncanonical target sequence in the FM enhancer, which drives transcription of Otx2, an essential player in rostral brain development []. Short Name:  TF_POU_3
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0 Child Features

5 Contains

DB identifier Type Name
IPR001356 Domain Homeobox domain
IPR010982 Domain Lambda repressor-like, DNA-binding domain
IPR000327 Domain POU-specific domain
IPR017970 Conserved_site Homeobox, conserved site
IPR013847 Domain POU domain

1 Cross References

Identifier
PIRSF002629

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003700 IPR016362
GO:0006357 IPR016362
GO:0007420 IPR016362
GO:0005634 IPR016362

4 Ontology Annotations

GO Term Gene Name
GO:0003700 IPR016362
GO:0006357 IPR016362
GO:0007420 IPR016362
GO:0005634 IPR016362

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1565620
            2739723
            22566684