Protein Domain : IPR015845

Type:  Family Name:  Agropine synthesis reductase
Description:  Several agrobacteria cause neoplastic diseases in plants, including crown gall disease (Agrobacterium tumefaciens) and hairy root disease (Agrobacterium rhizogenes). The mechanism involves transfer via infective plasmids and subsequent expression of both oncogenes and genes for the synthesis of opines, which can be specifically used as nutrients by the invading bacteria []. Opines are low molecular weight amino acid and sugar phosphate derivatives, e.g., octopine, agropine, and mannopine. The proteins in this group are products of the mas1genes (and homologues) encoding the reductase that produces mannopine from deoxyfructosylglutamine. Subsequently, mannopine can be lactonized to form agropine. The C-terminal short chain dehydrogenase domain () is coupled with an N-terminal phosphoglycerate mutase family domain (), the role of which is unknown []. Sequences reported from Ti plasmid pTiC58 are missing half [, ] or all of the N-terminal domain. Short Name:  Mas1

0 Child Features

2 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR020904 Conserved_site Short-chain dehydrogenase/reductase, conserved site

1 Cross References

Identifier
PIRSF036951

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016491 IPR015845
GO:0052007 IPR015845
GO:0055114 IPR015845

3 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR015845
GO:0052007 IPR015845
GO:0055114 IPR015845

1 Parent Features

DB identifier Type Name
IPR013078 Family Histidine phosphatase superfamily, clade-1

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Hyque.11G066900.1.p PAC:45858543 Hydrangea quercifolia 430  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11743194
            11743193
            12927971
            1909028