Protein Domain : IPR005933

Type:  Domain Name:  Delta-1-pyrroline-5-carboxylate dehydrogenase 3
Description:  The delta(1)-pyrroline-5-carboxylate synthetase () a mitochondrial inner membrane, ATP- and NADPH-dependent, bifunctional enzyme, catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline and ornithine. It is the rate-limiting enzyme in proline biosynthesis and is subject to feedback inhibition by proline.1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH This model represents one of several related branches of delta-1-pyrroline-5-carboxylate dehydrogenase. Members of this branch include the C-terminal domain of the PutA bifunctional proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase. Short Name:  Delta1-pyrroline-5-COlate_DH-3
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0 Child Features

2 Contains

DB identifier Type Name
IPR015590 Domain Aldehyde dehydrogenase domain
IPR016162 Domain Aldehyde dehydrogenase N-terminal domain

1 Cross References

Identifier
TIGR01238

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003842 IPR005933
GO:0006561 IPR005933
GO:0055114 IPR005933

3 Ontology Annotations

GO Term Gene Name
GO:0003842 IPR005933
GO:0006561 IPR005933
GO:0055114 IPR005933

0 Parent Features

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1007002m.p PAC:33620879 Brachypodium distachyon Pangenome 621  
Brdisv1BdTR11A1029384m.p PAC:35675406 Brachypodium distachyon BdTR11a 1199  
Brdisv1BdTR11A1041815m.p PAC:35694226 Brachypodium distachyon BdTR11a 1237  

0 Publications