Protein Domain : IPR006297

Type:  Family Name:  Elongation factor 4
Description:  Elongation factor 4, also known as ribosomal back-translocase LepA, is required for accurate and efficient protein synthesis under certain stress conditions. It may act as a fidelity factor of the translation reaction, by catalysing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly [, ]. Elongation factor 4 binds to ribosomes in a GTP-dependent manner.The eukaryotic homologue is known as GUF1 and promotes protein synthesis in chloroplasts and mitochondria []. Short Name:  EF-4
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1 Child Features

DB identifier Type Name
IPR027518 Family Translation factor GUF1 homologue, organellar chromatophore

6 Contains

DB identifier Type Name
IPR009022 Domain Elongation factor G, III-V domain
IPR000640 Domain Translation elongation factor EFG, V domain
IPR004161 Domain Translation elongation factor EFTu/EF1A, domain 2
IPR000795 Domain Transcription factor, GTP-binding domain
IPR009000 Domain Translation protein, beta-barrel domain
IPR013842 Domain GTP-binding protein LepA, C-terminal

2 Cross Referencess

Identifier
TIGR01393
MF_00071

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0005525 IPR006297

1 Ontology Annotations

GO Term Gene Name
GO:0005525 IPR006297

0 Parent Features

917 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
230251 D8QYJ7 PAC:15412347 Selaginella moellendorffii 647  
407721 D8R6J4 PAC:15421124 Selaginella moellendorffii 639  
evm.model.supercontig_37.74 PAC:16418749 Carica papaya 382  
29822.m003486 B9RUN8 PAC:16809855 Ricinus communis 673  
30225.m001722 B9RHQ5 PAC:16824211 Ricinus communis 693  
Cucsa.158430.1 PAC:16965121 Cucumis sativus 668  
orange1.1g008991m A0A067FYT1 PAC:18134990 Citrus sinensis 547  
orange1.1g008968m A0A067FYT1 PAC:18134991 Citrus sinensis 547  
AT5G08650.1 Q9FNM5 PAC:19671483 Arabidopsis thaliana 681  
AT5G39900.1 Q9FLE4 PAC:19667555 Arabidopsis thaliana 663  
Thhalv10027676m V4NKZ1 PAC:20189907 Eutrema salsugineum 663  
Thhalv10012870m V4KSA5 PAC:20204534 Eutrema salsugineum 679  
Thhalv10012924m V4LAX7 PAC:20204535 Eutrema salsugineum 650  
Ciclev10011231m V4UX40 PAC:20797826 Citrus clementina 675  
Ciclev10025061m V4SGH3 PAC:20800270 Citrus clementina 680  
Lus10025694 PAC:23177614 Linum usitatissimum 562  
Lus10015364 PAC:23160846 Linum usitatissimum 661  
Lus10035968 PAC:23141180 Linum usitatissimum 691  
Lus10007250 PAC:23165707 Linum usitatissimum 667  
Potri.001G305300.3 PAC:27047411 Populus trichocarpa 472  
Potri.001G305300.4 PAC:27047412 Populus trichocarpa 468  
Potri.001G305300.1 A0A2K2C667 PAC:27047409 Populus trichocarpa 678  
Potri.001G305300.2 PAC:27047410 Populus trichocarpa 553  
Potri.017G079800.4 PAC:26984153 Populus trichocarpa 614  
Potri.017G079800.3 PAC:26984154 Populus trichocarpa 609  
Potri.017G079800.1 B9IJU6 PAC:26984152 Populus trichocarpa 668  
Potri.017G079800.2 PAC:26984155 Populus trichocarpa 552  
Potri.017G079800.5 PAC:26984156 Populus trichocarpa 547  
Gorai.012G045200.1 A0A0D2V1U1 PAC:26827664 Gossypium raimondii 681  
Gorai.012G045200.2 A0A0D2RXT4 PAC:26827665 Gossypium raimondii 659  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17110332
            20045415
            18442968