3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0004345 | IPR001282 |
GO:0006006 | IPR001282 |
GO:0055114 | IPR001282 |
Type: | Family | Name: | Glucose-6-phosphate dehydrogenase |
Description: | Glucose-6-phosphate dehydrogenase () (G6PDH) is a ubiquitous protein, present in bacteria and all eukaryotic cell types []. The enzyme catalyses thethe first step in the pentose pathway, i.e. the conversion of glucose-6-phosphate to gluconolactone 6-phosphate in the presence of NADP, producing NADPH. The ubiquitous expression of the enzyme gives it a major role in the production of NADPH for the many NADPH-mediated reductive processes in all cells []. Deficiency of G6PDH is a common genetic abnormality affecting millions of people worldwide. Many sequence variants, most caused by single point mutations, are known, exhibiting a wide variety of phenotypes []. | Short Name: | G6P_DH |
GO Term | Gene Name |
---|---|
GO:0004345 | IPR001282 |
GO:0006006 | IPR001282 |
GO:0055114 | IPR001282 |