Protein Domain : IPR001174

Type:  Family Name:  Galactokinase/homoserine kinase
Description:  The lincomycin (LM)-production gene cluster of an over-producing strain of Streptomyces lincolnensishas been analysed []. The lmb/lmr gene cluster contains 27 open reading frames with putative biosynthetic or regulatory functions (lmb genes) and three resistance (lmr) genes []. Only a minority of the putative Lmb proteins belong to known protein families: these include members of the gamma-glutamyl transferases (LmbA);amino acid acylases (LmbC); aromatic amino acid aminotransferases (LmbF); imidazoleglycerolphosphate dehydratases (LmbK); dTDP-glucose synthases(LmbO); dTDP-glucose 4,6-dehydratases (LmbM); and (NDP-) ketohexose (or ketocyclitol) aminotransferases (LmbS) []. LmbP seems to show some similarity to a family of enzymes that share an N-terminal Gly/Ser-rich putative ATP-binding region: these include galacto-kinase (), homoserine kinase (), mevalonate kinase () and phosphomevalonate kinase []. Sequence v031 from Mycobacterium tuberculosis[] is also a homologue. Short Name:  Galkinase
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1 Child Features

DB identifier Type Name
IPR014606 Family D,D-heptose 7-phosphate kinase

4 Contains

DB identifier Type Name
IPR020568 Domain Ribosomal protein S5 domain 2-type fold
IPR013750 Domain GHMP kinase, C-terminal domain
IPR006204 Domain GHMP kinase N-terminal domain
IPR014721 Domain Ribosomal protein S5 domain 2-type fold, subgroup

1 Cross References

Identifier
PR00960

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005524 IPR001174
GO:0016301 IPR001174
GO:0008152 IPR001174

3 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR001174
GO:0016301 IPR001174
GO:0008152 IPR001174

0 Parent Features

824 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
413887 D8RQY4 PAC:15417639 Selaginella moellendorffii 339  
85034 D8R3R1 PAC:15416928 Selaginella moellendorffii 387  
evm.model.supercontig_139.7 PAC:16408571 Carica papaya 1091  
29742.m001375 B9SBD4 PAC:16807606 Ricinus communis 873  
29917.m002020 B9S667 PAC:16813623 Ricinus communis 354  
Cucsa.011170.1 A0A0A0KR19 PAC:16951384 Cucumis sativus 360  
Cucsa.099780.1 PAC:16958466 Cucumis sativus 355  
Cucsa.259420.2 PAC:16973011 Cucumis sativus 1034  
Cucsa.259420.1 PAC:16973010 Cucumis sativus 1085  
orange1.1g017756m A0A067FYW9 PAC:18099670 Citrus sinensis 366  
orange1.1g002861m A0A067H3U1 PAC:18135819 Citrus sinensis 873  
orange1.1g001402m A0A067H3E5 PAC:18135818 Citrus sinensis 1084  
AT1G01220.1 Q9LNJ9 PAC:19652890 Arabidopsis thaliana 1055  
AT2G17265.1 Q8L7R2 PAC:19643165 Arabidopsis thaliana 370  
Thhalv10022738m V4ME36 PAC:20201939 Eutrema salsugineum 370  
Thhalv10006637m V4LAG2 PAC:20187150 Eutrema salsugineum 1076  
Thhalv10004396m V4KQI5 PAC:20198297 Eutrema salsugineum 381  
Ciclev10001383m V4SFV0 PAC:20788738 Citrus clementina 398  
Ciclev10001381m V4SFV0 PAC:20788737 Citrus clementina 398  
Ciclev10001573m V4TAA0 PAC:20788740 Citrus clementina 367  
Ciclev10001545m V4T091 PAC:20788739 Citrus clementina 372  
Ciclev10028700m V4S5J7 PAC:20814630 Citrus clementina 366  
Ciclev10018702m V4VXC4 PAC:20807714 Citrus clementina 979  
Ciclev10015593m V4U1U9 PAC:20817003 Citrus clementina 383  
Lus10005982 PAC:23175073 Linum usitatissimum 1030  
Lus10030230 PAC:23153135 Linum usitatissimum 1073  
Lus10022282 PAC:23139439 Linum usitatissimum 345  
Lus10003665 PAC:23171442 Linum usitatissimum 345  
Potri.009G168400.1 A0A2K1Z932 PAC:26987026 Populus trichocarpa 366  
Potri.004G207000.1 B9MZ08 PAC:26991013 Populus trichocarpa 366  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1846667
            8577249
            8610181