Protein Domain : IPR011284

Type:  Family Name:  3-oxoacyl-(acyl-carrier-protein) reductase
Description:  This entry represents 3-oxoacyl-[ACP] reductase, also called 3-ketoacyl-acyl carrier protein reductase, an enzyme of fatty acid biosynthesis found in many plant and bacterial species. This enzyme is involved in type II fatty acid biosynthesis, where the individual metabolic transformations are carried out by different enzymes rather than by a single enzyme as occurs in type I fatty acid biosynthesis [].Structural studies show that the enzyme is a tetramer which forms a typical Rossman fold [, ]. Unlike other members of the short-chain dehydrogenase/reductase superfamily, the enzyme undergoes a marked conformational change upon binding of the NADP(H)cofactor. This conformational change aligns the side chains of the catalytic triad at the active site in an active conformation and increases the affinity of the enzyme for its substrate. Short Name:  3oxo_ACP_reduc
Paste the following link

0 Child Features

2 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR020904 Conserved_site Short-chain dehydrogenase/reductase, conserved site

1 Cross References

Identifier
TIGR01830

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004316 IPR011284
GO:0051287 IPR011284
GO:0006633 IPR011284
GO:0055114 IPR011284

4 Ontology Annotations

GO Term Gene Name
GO:0004316 IPR011284
GO:0051287 IPR011284
GO:0006633 IPR011284
GO:0055114 IPR011284

1 Parent Features

DB identifier Type Name
IPR002198 Family Short-chain dehydrogenase/reductase SDR

644 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
228168 D8RPM5 PAC:15405390 Selaginella moellendorffii 313  
29929.m004732 B9RMM7 PAC:16813971 Ricinus communis 328  
30147.m013777 B9RAK4 PAC:16819794 Ricinus communis 315  
Cucsa.394850.3 PAC:16983264 Cucumis sativus 279  
Cucsa.394850.1 A0A0A0LQU1 PAC:16983262 Cucumis sativus 329  
orange1.1g024338m A0A067H2R2 PAC:18102203 Citrus sinensis 269  
AT1G24360.1 P33207 PAC:19649964 Arabidopsis thaliana 319  
Thhalv10008469m V4MR04 PAC:20186750 Eutrema salsugineum 269  
Thhalv10008222m V4K932 PAC:20186749 Eutrema salsugineum 320  
Ciclev10032120m V4SU16 PAC:20803012 Citrus clementina 323  
Lus10036980 PAC:23171304 Linum usitatissimum 327  
Potri.010G056100.1 B9HTB3 PAC:26983089 Populus trichocarpa 324  
Potri.008G178700.1 PAC:27037329 Populus trichocarpa 329  
Potri.008G178700.2 A0A2K1ZJ45 PAC:27037330 Populus trichocarpa 325  
Gorai.008G164200.1 A0A0D2RGH9 PAC:26815745 Gossypium raimondii 320  
Gorai.009G333600.2 A0A0D2TZ69 PAC:26765147 Gossypium raimondii 324  
Gorai.009G333600.1 A0A0D2UXS1 PAC:26765146 Gossypium raimondii 326  
33281 I0YXT1 PAC:27392466 Coccomyxa subellipsoidea C-169 277  
55323 C1MKF9 PAC:27343158 Micromonas pusilla CCMP1545 310  
113389 C1FDQ2 PAC:27399280 Micromonas sp RCC299 329  
12103 A4RQY6 PAC:27417514 Ostreococcus lucimarinus 273  
Thecc1EG010763t1 A0A061E746 PAC:27464389 Theobroma cacao 326  
Migut.K00696.1.p A0A022QEC8 PAC:28937222 Mimulus guttatus 318  
Cagra.2625s0010.1.p PAC:28897196 Capsella grandiflora 319  
Glyma.08G102100.1.p I1KRZ2 PAC:30535757 Glycine max 299  
Glyma.11G248000.1.p K7LS11 PAC:30529098 Glycine max 320  
Glyma.11G248000.2.p I1LNB1 PAC:30529099 Glycine max 320  
Glyma.18G009200.1.p A0A0R0F5Q2 PAC:30554911 Glycine max 320  
Brara.G00869.1.p A0A397YJ97 PAC:30633074 Brassica rapa FPsc 319  
Brara.I03033.1.p A0A397Y0R3 PAC:30642768 Brassica rapa FPsc 320  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11669613
            11544358
            16225460