4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003743 | IPR000178 |
| GO:0005525 | IPR000178 |
| GO:0006413 | IPR000178 |
| GO:0005622 | IPR000178 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003743 | IPR000178 |
| GO:0005525 | IPR000178 |
| GO:0006413 | IPR000178 |
| GO:0005622 | IPR000178 |
| Type: | Family | Name: | Translation initiation factor aIF-2, bacterial-like |
| Description: | Initiation factor 2 (IF-2) (gene infB) [] is one of the three factorsrequired for the initiation of protein biosynthesis in bacteria. IF-2 promotes the GTP-dependent binding of the initiator tRNA to the small subunitof the ribosome. IF-2 is a protein of about 70 to 95 Kd which contains a central GTP-binding domain flanked by a highly variable N-terminal domain anda more conserved C-terminal domain. Bacterial IF-2 is structurally and functionally related to eukaryoticmitochondrial IF-2 (IF-2(mt)) [] as well as to algal and plants chloroplastIF-2 (IF-2(chl)). Both IF-2(mt) and IF-2(chl) are encoded by nuclear genes and are produced as precursor proteins with a transit peptide. An exception arered algae where IF-2(chl) is encoded by the plastid genome [].This model discriminates eubacterial (and mitochondrial) translation initiation factor 2 (IF-2), encoded by the infB gene in bacteria, from similar proteins in the Archaea and Eukaryotes. In the bacteria and in organelles, the initiator tRNA is charged with N-formyl-Met instead of Met. This translation factor acts in delivering the initator tRNA to the ribosome. It is one of a number of GTP-binding translation factors recognised by the pfam HMM GTP_EFTU. | Short Name: | TF_IF2_bacterial-like |
| GO Term | Gene Name |
|---|---|
| GO:0003743 | IPR000178 |
| GO:0005525 | IPR000178 |
| GO:0006413 | IPR000178 |
| GO:0005622 | IPR000178 |
| GO Term | Gene Name |
|---|---|
| GO:0003743 | IPR000178 |
| GO:0005525 | IPR000178 |
| GO:0006413 | IPR000178 |
| GO:0005622 | IPR000178 |
