Protein Domain : IPR004837

Type:  Domain Name:  Sodium/calcium exchanger membrane region
Description:  The sodium/calcium exchangers are a family of integral membrane proteins. This domain covers the integral membrane regions of these proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells []. Ca2+ is moved into or out of the cytosol depending on Na+ concentration []. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3 []. Short Name:  NaCa_Exmemb
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0 Child Features

0 Contains

1 Cross References

Identifier
PF01699

4 Found Ins

DB identifier Type Name
IPR004713 Family Calcium/proton exchanger
IPR004798 Family Calcium/proton exchanger CAX
IPR004481 Family Sodium/potassium/calcium exchanger
IPR004836 Family Sodium/calcium exchanger protein

2 GO Annotations

GO Term Gene Name
GO:0055085 IPR004837
GO:0016021 IPR004837

2 Ontology Annotations

GO Term Gene Name
GO:0055085 IPR004837
GO:0016021 IPR004837

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
404613 D8QVW0 PAC:15411685 Selaginella moellendorffii 628  
52345 D8RTD9 PAC:15411238 Selaginella moellendorffii 525  
111442 D8S8I3 PAC:15410461 Selaginella moellendorffii 147  
82507 D8R2N6 PAC:15411909 Selaginella moellendorffii 348  
84653 D8R3I1 PAC:15418624 Selaginella moellendorffii 412  
42348 D8SVX6 PAC:15403862 Selaginella moellendorffii 531  
89075 D8RBT7 PAC:15406337 Selaginella moellendorffii 590  
76965 D8QSR8 PAC:15419584 Selaginella moellendorffii 546  
92047 D8RER9 PAC:15415436 Selaginella moellendorffii 600  
evm.TU.contig_37389.1 PAC:16431024 Carica papaya 354  
evm.model.supercontig_11.155 PAC:16405646 Carica papaya 451  
evm.model.supercontig_12.88 PAC:16406931 Carica papaya 415  
evm.model.supercontig_131.74 PAC:16408072 Carica papaya 586  
evm.model.supercontig_131.78 PAC:16408076 Carica papaya 723  
evm.model.supercontig_161.37 PAC:16410207 Carica papaya 572  
evm.model.supercontig_25.133 PAC:16414727 Carica papaya 662  
evm.model.supercontig_415.5 PAC:16419661 Carica papaya 427  
evm.model.supercontig_48.27 PAC:16420884 Carica papaya 566  
evm.model.supercontig_7.24 PAC:16425153 Carica papaya 544  
evm.model.supercontig_73.1 PAC:16425585 Carica papaya 493  
evm.model.supercontig_9.258 PAC:16428155 Carica papaya 540  
29701.m000596 B9SQ31 PAC:16806128 Ricinus communis 449  
29739.m003745 B9RR92 PAC:16807523 Ricinus communis 668  
29748.m000386 B9SAK3 PAC:16807781 Ricinus communis 265  
29862.m000338 B9S836 PAC:16811661 Ricinus communis 543  
29862.m000339 B9S837 PAC:16811662 Ricinus communis 588  
29900.m001571 B9S959 PAC:16812450 Ricinus communis 521  
29986.m001622 B9SAS2 PAC:16815120 Ricinus communis 1015  
30005.m001242 B9SEZ0 PAC:16815475 Ricinus communis 448  
30072.m000938 B9SI62 PAC:16816728 Ricinus communis 576  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8798769
            1700476