Protein Domain : IPR029058

Type:  Domain Name:  Alpha/Beta hydrolase fold
Description:  This entry represent the Alpha/Beta hydrolase fold. The alpha/beta hydrolase fold [] is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices []. The enzymes are believed to have diverged from a common ancestor, preserving the arrangement of the catalytic residues. All have a catalytic triad, the elements of which are borne on loops, which are the best conserved structural features of the fold. Esterase (EST) from Pseudomonas putidais a member of the alpha/beta hydrolase fold superfamily of enzymes [].In most of the family members the beta-strands are parallels, but some have an inversion of the first strands, which gives it an antiparallel orientation. The catalytic triad residues are presented on loops. One of these is the nucleophile elbow and is the most conserved feature of the fold. Some other members lack one or all of the catalytic residues. Some members are therefore inactive but others are involved in surface recognition. The ESTHER database [] gathers and annotates all the published information related to gene and protein sequences of this superfamily []. Short Name:  AB_hydrolase
Paste the following link

14 Child Features

DB identifier Type Name
IPR000073 Domain Alpha/beta hydrolase fold-1
IPR029059 Domain Alpha/beta hydrolase fold-5
IPR001375 Domain Peptidase S9, prolyl oligopeptidase, catalytic domain
IPR002921 Domain Fungal lipase-like domain
IPR013094 Domain Alpha/beta hydrolase fold-3
IPR003140 Domain Phospholipase/carboxylesterase/thioesterase
IPR000383 Domain Xaa-Pro dipeptidyl-peptidase-like domain
IPR002925 Domain Dienelactone hydrolase
IPR002018 Domain Carboxylesterase, type B
IPR001031 Domain Thioesterase
IPR008391 Domain Acetyl xylan esterase
IPR010333 Domain Bacterial virulence
IPR000675 Domain Cutinase
IPR013818 Domain Lipase, N-terminal

0 Contains

2 Cross Referencess

Identifier
G3DSA:3.40.50.1820
SSF53474

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

141653 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
430261 D8T8V4 PAC:15418609 Selaginella moellendorffii 218  
410871 D8RG49 PAC:15408762 Selaginella moellendorffii 238  
440881 D8RF48 PAC:15407989 Selaginella moellendorffii 432  
92150 D8RF38 PAC:15416166 Selaginella moellendorffii 391  
92383 D8REZ7 PAC:15417744 Selaginella moellendorffii 356  
92683 D8RGA7 PAC:15420028 Selaginella moellendorffii 318  
92534 D8RFX8 PAC:15419167 Selaginella moellendorffii 297  
430655 D8TA30 PAC:15421518 Selaginella moellendorffii 260  
65425 D8RGI5 PAC:15405486 Selaginella moellendorffii 273  
64764 D8RH01 PAC:15404903 Selaginella moellendorffii 327  
93236 D8RGY0 PAC:15419782 Selaginella moellendorffii 283  
24191 D8TAU5 PAC:15416337 Selaginella moellendorffii 280  
24539 D8TAV1 PAC:15419272 Selaginella moellendorffii 282  
430924 D8TAZ3 PAC:15401509 Selaginella moellendorffii 469  
4371 D8TAW9 PAC:15415153 Selaginella moellendorffii 226  
411520 D8RI73 PAC:15409331 Selaginella moellendorffii 242  
441284 D8RI89 PAC:15406405 Selaginella moellendorffii 742  
431536 D8TCZ4 PAC:15401388 Selaginella moellendorffii 193  
137360 D8TDD2 PAC:15419308 Selaginella moellendorffii 243  
12596 D8RK91 PAC:15406327 Selaginella moellendorffii 427  
172238 D8RKL6 PAC:15410370 Selaginella moellendorffii 368  
441581 D8RKT9 PAC:15408685 Selaginella moellendorffii 131  
412336 D8RKU0 PAC:15410804 Selaginella moellendorffii 131  
96010 D8RK88 PAC:15404534 Selaginella moellendorffii 399  
95625 D8RK84 PAC:15406306 Selaginella moellendorffii 396  
137638 D8TDZ6 PAC:15421403 Selaginella moellendorffii 282  
96082 D8RKM6 PAC:15404698 Selaginella moellendorffii 276  
172410 D8RLK3 PAC:15411845 Selaginella moellendorffii 619  
96553 D8RLK6 PAC:15408511 Selaginella moellendorffii 610  
96419 D8RLJ4 PAC:15407601 Selaginella moellendorffii 465  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1409539
            16321951
            14681380