3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008667 | IPR003560 |
| GO:0019290 | IPR003560 |
| GO:0055114 | IPR003560 |
| Type: | Family | Name: | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase |
| Description: | The absence of free iron molecules in the surrounding environment triggers transcription of gene clusters that encode both siderophore-synthesis enzymes, and receptors that recognise iron-bound siderophores []. Classic examples are the enterobactin/enterochelin clusters found in Escherichia coliand Salmonella, although similar moieties in other pathogens have been identified. The enzymic machinery that produces vibrionectin in Vibrio choleraeis such a homologue [].EntA, a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase enzyme, is the third enzyme in the biosynthesis of 2,3-dihydroxybenzoic acid (DHB) from chorismate in Escherichia coli. It converts isochorismate to DHB, used for the synthesis of iron chelator enterobactin. Bacillus subtilis possesses similar genes involved in siderophore biosynthesis []. Deletion studies involving EntA-mutants have shown that it is essential for virulence []. | Short Name: | DHB_DH |
| GO Term | Gene Name |
|---|---|
| GO:0008667 | IPR003560 |
| GO:0019290 | IPR003560 |
| GO:0055114 | IPR003560 |
