Protein Domain : IPR011859

Type:  Family Name:  Dihydrodipicolinate reductase, plant-type
Description:  Dihydrodipicolinate reductase is an enzyme found in bacteria and higher plants which is involved in the biosynthesis of diaminopimelic acid, a component of bacterial cell walls, and the essential amino acid L-lysine. It catalyses the the reduced pyridine nucleotide-dependent reduction of the alpha,beta-unsaturated cyclic imine, dihydrodipicolinate, to generate tetrahydrodipicolinate as shown below []:2,3-dihydrodipicolinate + NAD(P)H = 2,3,4,5-tetrahydrodipicolinate + NAD(P)(+)As this enzyme is not found in mammals it is a potential target for the development of novel antibacterial and herbicidal compounds.This narrow family includes genes from Arabidopsis and Fibrobacter succinogenes(Bacteroides succinogenes) (which probably recieved the gene from a plant via lateral gene transfer). The sequences are distantly related to the dihydrodipicolinate reductases from archaea. In Fibrobacter this gene is the only candidate DHPR in the genome. Short Name:  Dihydrodipicolinate_Rdtase_pln
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0 Child Features

2 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR022663 Domain Dihydrodipicolinate reductase, C-terminal

1 Cross References

Identifier
TIGR02130

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0008839 IPR011859
GO:0070402 IPR011859
GO:0009089 IPR011859
GO:0055114 IPR011859

4 Ontology Annotations

GO Term Gene Name
GO:0008839 IPR011859
GO:0070402 IPR011859
GO:0009089 IPR011859
GO:0055114 IPR011859

0 Parent Features

686 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
168311 D8R6G2 PAC:15421275 Selaginella moellendorffii 288  
evm.model.supercontig_182.24 PAC:16411575 Carica papaya 386  
28266.m000195 B9T529 PAC:16800458 Ricinus communis 354  
Cucsa.007160.1 PAC:16951205 Cucumis sativus 362  
orange1.1g024671m A0A067D771 PAC:18134868 Citrus sinensis 264  
orange1.1g028115m A0A067DFH4 PAC:18134869 Citrus sinensis 213  
AT3G59890.1 Q8LB01 PAC:19663782 Arabidopsis thaliana 349  
AT3G59890.2 Q8LB01 PAC:19663783 Arabidopsis thaliana 343  
AT2G44040.1 O80574 PAC:19642463 Arabidopsis thaliana 347  
Thhalv10006083m V4L1E9 PAC:20190629 Eutrema salsugineum 338  
Thhalv10001534m V4KMD1 PAC:20188868 Eutrema salsugineum 341  
Ciclev10020914m V4TPC8 PAC:20810644 Citrus clementina 349  
Lus10041701 PAC:23146716 Linum usitatissimum 337  
Lus10024047 PAC:23141437 Linum usitatissimum 321  
Potri.017G001900.1 U5FL60 PAC:26985614 Populus trichocarpa 325  
Potri.007G145900.1 A0A3N7GKW1 PAC:27016191 Populus trichocarpa 324  
Gorai.001G202100.2 A0A0D2PUD2 PAC:26824885 Gossypium raimondii 339  
Gorai.001G202100.3 A0A0D2QT96 PAC:26824886 Gossypium raimondii 327  
Gorai.001G202100.4 A0A0D2M0Z4 PAC:26824887 Gossypium raimondii 264  
Gorai.001G202100.1 A0A0D2Q1P9 PAC:26824884 Gossypium raimondii 358  
Gorai.007G347100.1 A0A0D2SVL1 PAC:26783190 Gossypium raimondii 339  
11516 I0Z8S3 PAC:27389056 Coccomyxa subellipsoidea C-169 274  
125443 C1MYX7 PAC:27344114 Micromonas pusilla CCMP1545 282  
82373 C1E7M8 PAC:27402382 Micromonas sp RCC299 295  
40454 A4S841 PAC:27417280 Ostreococcus lucimarinus 300  
Thecc1EG001303t1 A0A061DK14 PAC:27437303 Theobroma cacao 339  
Thecc1EG001303t2 A0A061DK14 PAC:27437304 Theobroma cacao 339  
Migut.M00539.2.p A0A022RMI7 PAC:28949168 Mimulus guttatus 349  
Migut.M00539.1.p A0A022RMI7 PAC:28949169 Mimulus guttatus 349  
Migut.M00539.3.p A0A022RL55 PAC:28949171 Mimulus guttatus 328  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8993314