Protein Domain : IPR012599

Type:  Domain Name:  Peptidase C1A, propeptide
Description:  This domain is found at the N-terminal of cathepsin B and cathepsin B-like peptidases that belong to MEROPS peptidase subfamily C1A. Cathepsin B are lysosomal cysteine proteinases belonging to the papain superfamily and are unique in their ability to act as both an endo- and an exopeptidases. They are synthesized as inactive zymogens. Activation of the peptidases occurs with the removal of the propeptide [, ]. Short Name:  Propeptide_C1A
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0 Child Features

0 Contains

1 Cross References

Identifier
PF08127

2 Found Ins

DB identifier Type Name
IPR013128 Family Peptidase C1A
IPR015643 Family Peptidase C1A, cathepsin B

2 GO Annotations

GO Term Gene Name
GO:0004197 IPR012599
GO:0050790 IPR012599

2 Ontology Annotations

GO Term Gene Name
GO:0004197 IPR012599
GO:0050790 IPR012599

0 Parent Features

556 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
143272 D8R361 PAC:15414159 Selaginella moellendorffii 331  
evm.model.supercontig_57.55 PAC:16422878 Carica papaya 323  
30076.m004510 B9RN00 PAC:16817123 Ricinus communis 376  
Cucsa.340620.7 PAC:16979087 Cucumis sativus 348  
Cucsa.340620.1 PAC:16979081 Cucumis sativus 351  
Cucsa.340620.2 A0A0A0LFN4 PAC:16979082 Cucumis sativus 349  
orange1.1g018568m A0A067H408 PAC:18137608 Citrus sinensis 354  
orange1.1g018707m A0A067HFS1 PAC:18137609 Citrus sinensis 351  
orange1.1g018877m A0A067HFG6 PAC:18137610 Citrus sinensis 349  
orange1.1g023657m A0A067H730 PAC:18137612 Citrus sinensis 279  
orange1.1g022267m A0A067H4G3 PAC:18137611 Citrus sinensis 300  
AT4G01610.1 Q94K85 PAC:19646602 Arabidopsis thaliana 359  
AT4G01610.2 Q94K85 PAC:19646603 Arabidopsis thaliana 359  
AT1G02300.1 F4HVZ1 PAC:19651664 Arabidopsis thaliana 379  
AT1G02305.1 Q93VC9 PAC:19655879 Arabidopsis thaliana 362  
Thhalv10028753m V4MYX4 PAC:20197672 Eutrema salsugineum 362  
Thhalv10008009m V4MWI3 PAC:20185964 Eutrema salsugineum 360  
Ciclev10020859m V4TC47 PAC:20807278 Citrus clementina 354  
Lus10007212 PAC:23167581 Linum usitatissimum 518  
Lus10010091 PAC:23158913 Linum usitatissimum 678  
Potri.002G184300.4 PAC:27022916 Populus trichocarpa 407  
Potri.002G184300.3 A0A2K2BKU1 PAC:27022918 Populus trichocarpa 373  
Potri.002G184300.1 PAC:27022917 Populus trichocarpa 407  
Potri.002G184300.2 PAC:27022919 Populus trichocarpa 330  
Potri.002G184200.1 PAC:27023394 Populus trichocarpa 356  
Potri.002G184200.2 PAC:27023395 Populus trichocarpa 325  
Potri.014G109800.1 PAC:27034949 Populus trichocarpa 352  
Gorai.007G055400.2 A0A0D2S7F4 PAC:26783536 Gossypium raimondii 354  
Gorai.007G055400.1 A0A0D2T9D2 PAC:26783535 Gossypium raimondii 355  
Gorai.007G115600.1 A0A0D2QR18 PAC:26785528 Gossypium raimondii 357  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7890671
            8740363