GO Term : GO:0004197 cysteine-type endopeptidase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004197 143272  
OntologyAnnotation GO:0004197 143272 GO
GOAnnotation GO:0004197 89437  
OntologyAnnotation GO:0004197 89437 GO
GOAnnotation GO:0004197 430194  
OntologyAnnotation GO:0004197 430194 GO
OntologyAnnotation GO:0004197 270839 GO
GOAnnotation GO:0004197 270839  
GOAnnotation GO:0004197 104486  
OntologyAnnotation GO:0004197 104486 GO
GOAnnotation GO:0004197 104974  
OntologyAnnotation GO:0004197 104974 GO
OntologyAnnotation GO:0004197 152567 GO
GOAnnotation GO:0004197 152567  
OntologyAnnotation GO:0004197 evm.model.supercontig_13.214 GO
GOAnnotation GO:0004197 evm.TU.supercontig_13.214  
OntologyAnnotation GO:0004197 evm.model.supercontig_166.50 GO
GOAnnotation GO:0004197 evm.TU.supercontig_166.50  
GOAnnotation GO:0004197 evm.TU.supercontig_190.38  
OntologyAnnotation GO:0004197 evm.model.supercontig_190.38 GO
OntologyAnnotation GO:0004197 evm.model.supercontig_32.144 GO
GOAnnotation GO:0004197 evm.TU.supercontig_32.144  
GOAnnotation GO:0004197 evm.TU.supercontig_33.175  
OntologyAnnotation GO:0004197 evm.model.supercontig_33.175 GO
GOAnnotation GO:0004197 evm.TU.supercontig_42.39  
OntologyAnnotation GO:0004197 evm.model.supercontig_42.40 GO
OntologyAnnotation GO:0004197 evm.model.supercontig_42.39 GO
GOAnnotation GO:0004197 evm.TU.supercontig_42.40  
OntologyAnnotation GO:0004197 evm.model.supercontig_52.79 GO
GOAnnotation GO:0004197 evm.TU.supercontig_52.79  

15 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0004197 cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

66 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004175 GO:0004197
is_a GO:0008234 GO:0004197
part of GO:0006508 GO:0004197
part of GO:0008152 GO:0004197
is_a GO:0070011 GO:0004197
is_a GO:0016787 GO:0004197
part of GO:0043170 GO:0004197
part of GO:0019538 GO:0004197
is_a GO:0003824 GO:0004197
part of GO:0044238 GO:0004197
part of GO:0071704 GO:0004197
is_a GO:0008233 GO:0004197
is_a GO:0003674 GO:0004197
part of GO:0008150 GO:0004197
is_a GO:0004197 GO:0004198
positively regulates GO:0004197 GO:0006919
regulates GO:0004197 GO:0006919
positively regulates GO:0004197 GO:0008635
regulates GO:0004197 GO:0008635
negatively regulates GO:0004197 GO:0039650
regulates GO:0004197 GO:0039650
positively regulates GO:0004197 GO:0039651
regulates GO:0004197 GO:0039651
regulates GO:0004197 GO:0043154
negatively regulates GO:0004197 GO:0043154
regulates GO:0004197 GO:0043280
positively regulates GO:0004197 GO:0043280
regulates GO:0004197 GO:0043281
is_a GO:0004197 GO:0070137
is_a GO:0004197 GO:0070139

4 Synonyms

Name Type
metacaspase activity synonym
caspase activity synonym
lysosomal cysteine-type endopeptidase synonym
thiol endopeptidase activity synonym