GO Term : GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process GO
Namespace:  molecular_function Obsolete:  false
description  Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

18 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004222 metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008237 metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0042987 amyloid precursor protein catabolic process The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
GO:0042982 amyloid precursor protein metabolic process The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.

27 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0004222 GO:1902945
part of GO:0042987 GO:1902945
is_a GO:0004222 GO:1902945
part of GO:0042987 GO:1902945
part of GO:0043170 GO:1902945
is_a GO:0016787 GO:1902945
part of GO:0006508 GO:1902945
is_a GO:0003824 GO:1902945
is_a GO:0070011 GO:1902945
part of GO:0071704 GO:1902945
part of GO:0019538 GO:1902945
part of GO:0008150 GO:1902945
part of GO:0042982 GO:1902945
is_a GO:0008237 GO:1902945
part of GO:0008152 GO:1902945
is_a GO:0003674 GO:1902945
is_a GO:0008233 GO:1902945
is_a GO:0004175 GO:1902945
part of GO:0044238 GO:1902945
regulates GO:1902945 GO:1902962
regulates GO:1902945 GO:1902962
negatively regulates GO:1902945 GO:1902963
negatively regulates GO:1902945 GO:1902963
regulates GO:1902945 GO:1902963
positively regulates GO:1902945 GO:1902964
positively regulates GO:1902945 GO:1902964
regulates GO:1902945 GO:1902964

17 Synonyms

Name Type
metalloendopeptidase activity involved in amyloid precursor protein catabolism synonym
metalloendopeptidase activity involved in amyloid precursor protein breakdown synonym
metalloendopeptidase activity involved in APP catabolic process synonym
metalloendopeptidase activity involved in amyloid precursor protein degradation synonym
metalloendoprotease activity involved in amyloid precursor protein breakdown synonym
metalloendopeptidase activity involved in APP catabolism synonym
metalloendoprotease activity involved in amyloid precursor protein catabolism synonym
metalloendoprotease activity involved in amyloid precursor protein catabolic process synonym
metalloendoprotease activity involved in APP catabolic process synonym
metalloendoprotease activity involved in amyloid precursor protein degradation synonym
metalloendoproteinase activity involved in amyloid precursor protein breakdown synonym
metalloendoprotease activity involved in APP catabolism synonym
metalloendoproteinase activity involved in amyloid precursor protein catabolism synonym
metalloendoproteinase activity involved in amyloid precursor protein catabolic process synonym
metalloendoproteinase activity involved in APP catabolic process synonym
metalloendoproteinase activity involved in amyloid precursor protein degradation synonym
metalloendoproteinase activity involved in APP catabolism synonym