116 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0005515 | protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
| GO:0000989 | transcription factor activity, transcription factor binding | Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. |
| GO:0005488 | binding | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
| GO:0006355 | regulation of transcription, DNA-templated | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| GO:0008152 | metabolic process | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
| GO:0009058 | biosynthetic process | The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
| GO:0045892 | negative regulation of transcription, DNA-templated | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| GO:0006352 | DNA-templated transcription, initiation | Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. |
| GO:0044237 | cellular metabolic process | The chemical reactions and pathways by which individual cells transform chemical substances. |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. |
| GO:0003712 | transcription cofactor activity | Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery. |
| GO:0006351 | transcription, DNA-templated | The cellular synthesis of RNA on a template of DNA. |
| GO:0006807 | nitrogen compound metabolic process | The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. |
| GO:0006139 | nucleobase-containing compound metabolic process | Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
| GO:0010468 | regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
| GO:0071704 | organic substance metabolic process | The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
| GO:0001104 | RNA polymerase II transcription cofactor activity | Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery. |
| GO:0051252 | regulation of RNA metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. |
| GO:0003713 | transcription coactivator activity | Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery. |
| GO:0044238 | primary metabolic process | The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
| GO:0006725 | cellular aromatic compound metabolic process | The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. |
| GO:0006366 | transcription from RNA polymerase II promoter | The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). |
| GO:0016070 | RNA metabolic process | The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
| GO:0044249 | cellular biosynthetic process | The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. |
| GO:0009059 | macromolecule biosynthetic process | The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
| GO:0045893 | positive regulation of transcription, DNA-templated | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| GO:0044260 | cellular macromolecule metabolic process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
| GO:0008134 | transcription factor binding | Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription. |
| GO:0009890 | negative regulation of biosynthetic process | Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. |
147 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0051123 | GO:0001128 |
| is_a | GO:0001105 | GO:0001128 |
| part of | GO:0006351 | GO:0001128 |
| is_a | GO:0098811 | GO:0001128 |
| part of | GO:0006352 | GO:0001128 |
| part of | GO:0009987 | GO:0001128 |
| is_a | GO:0001104 | GO:0001128 |
| part of | GO:0071840 | GO:0001128 |
| part of | GO:0016043 | GO:0001128 |
| part of | GO:0046483 | GO:0001128 |
| regulates | GO:0034654 | GO:0001128 |
| part of | GO:0000122 | GO:0001128 |
| part of | GO:0043933 | GO:0001128 |
| part of | GO:0009059 | GO:0001128 |
| regulates | GO:0071704 | GO:0001128 |
| part of | GO:0031326 | GO:0001128 |
| part of | GO:0031327 | GO:0001128 |
| part of | GO:0031324 | GO:0001128 |
| part of | GO:0031325 | GO:0001128 |
| part of | GO:0032774 | GO:0001128 |
| part of | GO:0031323 | GO:0001128 |
| has_part | GO:0008134 | GO:0001128 |
| regulates | GO:0009058 | GO:0001128 |
| regulates | GO:0009059 | GO:0001128 |
| part of | GO:0031328 | GO:0001128 |
| regulates | GO:1901360 | GO:0001128 |
| regulates | GO:0046483 | GO:0001128 |
| part of | GO:0006357 | GO:0001128 |
| part of | GO:0010604 | GO:0001128 |
| part of | GO:0044238 | GO:0001128 |
