| Type: | Conserved_site | Name: | Uncharacterised protein family UPF0029, Impact, conserved site |
| Description: | This entry contains the protein Impact, which is a translational regulator that ensures constant high levels of translation under amino acid starvation. It acts by interacting with Gcn1/Gcn1L1, thereby preventing activation of Gcn2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. It is evolutionary conserved from eukaryotes to archaea []. This signature pattern matches a conserved region. | Short Name: | UPF0029_Impact_CS |
