Protein Domain : IPR020453

Type:  Family Name:  Interleukin-22
Description:  Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells. This entry represents Interleukin-22 (IL-22), that belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26 []. It is produced by activated T cells and acts as a T cell mediator, promoting the innate, non-specific immunity of tissues []. IL-22 also regulates early defence mechanisms against attaching and effacing (A/E) bacterial pathogens []. This entry represents interleukin-22. Short Name:  IL-22

0 Child Features

2 Contains

DB identifier Type Name
IPR012351 Domain Four-helical cytokine, core
IPR020423 Conserved_site Interleukin-10, conserved site

3 Cross Referencess

Identifier
PF14565
PIRSF037726
PR01936

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0005576 IPR020453

1 Ontology Annotations

GO Term Gene Name
GO:0005576 IPR020453

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11929132
            15308104
            18264109